Yeo Quan You, Kee Kwek Ernest Beng
Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore.
J Clin Orthop Trauma. 2019 Jul-Aug;10(4):789-791. doi: 10.1016/j.jcot.2018.08.014. Epub 2018 Aug 10.
In recent years, the increase in utilisation of bone substitutes in the reconstruction of bone defects has been fuelled by donor site complications associated with autologous bone harvesting. However the ability of bone substitute to stimulate bone union while maintaining fracture reduction has been a topic of debate. Cerament Bone Void Filler (CBVF) is a novel biphasic and injectable ceramic bone substitute that has high compressive strength and the ability to promote cancellous bone healing.
This is a retrospective study to evaluate the surgical outcome of utilising CBVF in the treatment of depressed metaphyseal bone fractures over a two year period. The patients were followed up for at least six months after surgery and clinical parameters such as wound site complications were collated. Radiographic imaging was evaluated to determine loss of fracture reduction and rate of cement resorption.
Thirteen patients with depressed metaphyseal fractures were enrolled, which included: (i) one proximal humerus fracture; (ii) three tibial plateau fractures; and (iii) nine calcaneal fractures. None of the patients showed significant collapse in fracture reduction after six months of follow up. Cement resorption was noted in one patient as early as three weeks after surgery. There were no cases of cement leak or wound site complications.
Cerament Bone Void Filler (CBVF) is a promising bone graft substitute in the management of depressed metaphyseal bone fractures, with the ability to maintain fracture reduction despite cement resorption.
近年来,与自体骨采集相关的供区并发症推动了骨替代物在骨缺损重建中应用的增加。然而,骨替代物在维持骨折复位的同时刺激骨愈合的能力一直是一个有争议的话题。Cerament骨缺损填充剂(CBVF)是一种新型的双相可注射陶瓷骨替代物,具有高抗压强度和促进松质骨愈合的能力。
这是一项回顾性研究,旨在评估在两年期间使用CBVF治疗干骺端凹陷性骨折的手术效果。术后对患者进行至少六个月的随访,并整理伤口部位并发症等临床参数。评估影像学检查结果以确定骨折复位丢失情况和骨水泥吸收速率。
纳入13例干骺端凹陷性骨折患者,其中包括:(i)1例肱骨近端骨折;(ii)3例胫骨平台骨折;以及(iii)9例跟骨骨折。随访六个月后,所有患者均未出现明显的骨折复位塌陷。有1例患者在术后三周就出现了骨水泥吸收。未发生骨水泥渗漏或伤口部位并发症。
Cerament骨缺损填充剂(CBVF)在治疗干骺端凹陷性骨折方面是一种有前景的骨移植替代物,尽管存在骨水泥吸收,但仍有维持骨折复位的能力。