有机磷中毒所致中毒性脊髓神经病：3例青少年患者系列报道及简要综述
Organophosphorus-Induced Toxic Myeloneuropathy: Series of Three Adolescent Patients with Short Review.
作者信息
Nayak Priyabrata, Mallick Ashok K, Mishra Shubhankar, Panigrahy Debasish
机构信息
Department of Neurology, Sriram Chandra Bhanja (S.C.B.) Medical College, Cuttack, Odisha, India.
出版信息
J Pediatr Neurosci. 2019 Jan-Mar;14(1):42-45. doi: 10.4103/jpn.JPN_45_18.
Abstract
Organophosphate (OP) poisoning is the most common poisoning in India, accounting for almost half of the hospital admissions due to poisoning. Delayed neuropathy is initiated by an attack on a nervous tissue esterase. Although uncommon, delayed neurotoxicity has been consistently reported in literature. This mechanism is implicated not only in damaging peripheral nervous system but also in causing central processes leading to myelopathy. We report a series of three adolescent patients who came to our hospital with delayed neurological manifestations of organophosphorus poisoning, which came out to be OP-induced myeloneuropathy after detailed analysis and evaluation.
摘要
有机磷中毒是印度最常见的中毒类型，几乎占中毒导致住院人数的一半。迟发性神经病是由对神经组织酯酶的攻击引发的。尽管并不常见，但迟发性神经毒性在文献中一直有报道。这种机制不仅与损伤周围神经系统有关，还与导致脊髓病的中枢过程有关。我们报告了三名青少年患者，他们因有机磷中毒的迟发性神经表现前来我院就诊，经过详细分析和评估，结果显示为有机磷诱发的脊髓神经病。
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