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Simultaneous Liver-Kidney Transplant: Long-Term Management (Steroid Withdrawal and Safety Net Patients).

作者信息

Wiseman Alexander C

机构信息

Division of Nephrology University of Colorado Anschutz Medical Campus Aurora CO.

出版信息

Clin Liver Dis (Hoboken). 2019 Jul 2;13(6):176-179. doi: 10.1002/cld.814. eCollection 2019 Jun.

DOI:10.1002/cld.814
PMID:31316765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6605733/
Abstract
摘要

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Simultaneous Liver-Kidney Transplant: Long-Term Management (Steroid Withdrawal and Safety Net Patients).肝肾联合移植：长期管理（停用类固醇及安全网患者）
Clin Liver Dis (Hoboken). 2019 Jul 2;13(6):176-179. doi: 10.1002/cld.814. eCollection 2019 Jun.
2
Steroid withdrawal in pancreas transplant recipients.胰腺移植受者的类固醇撤药
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3
Steroid withdrawal in kidney transplant recipients: is it a safe option?肾移植受者停用类固醇：这是一个安全的选择吗？
Clin Transplant. 1997 Oct;11(5 Pt 2):500-4.
4
Prospective randomized trial of steroid withdrawal in liver transplant patients: preliminary report.
Transpl Int. 1994;7 Suppl 1:S88-90. doi: 10.1111/j.1432-2277.1994.tb01317.x.
5
Late steroid withdrawal for renal transplant recipients on tacrolimus and MMF is safe.对于接受他克莫司和霉酚酸酯治疗的肾移植受者，晚期停用类固醇是安全的。
Transplant Proc. 2005 May;37(4):1795-6. doi: 10.1016/j.transproceed.2005.02.094.
6
Steroid avoidance or withdrawal for kidney transplant recipients.肾移植受者停用或撤减类固醇
Cochrane Database Syst Rev. 2009 Jan 21(1):CD005632. doi: 10.1002/14651858.CD005632.pub2.
7
Steroid withdrawal based on lymphocyte sensitivity to endogenous steroid in renal transplant recipients.基于肾移植受者淋巴细胞对内源性类固醇敏感性的类固醇撤药。
Biol Pharm Bull. 2011;34(10):1578-83. doi: 10.1248/bpb.34.1578.
8
Early steroid withdrawal in solitary pancreas transplantation results in equivalent graft and patient survival compared with maintenance steroid therapy.与维持性类固醇治疗相比，孤立胰腺移植中早期停用类固醇可使移植物和患者生存率相当。
Clin Transplant. 2007 Jul-Aug;21(4):491-7. doi: 10.1111/j.1399-0012.2007.00675.x.
9
Early steroid withdrawal compared with steroid avoidance correlates with graft failure among kidney transplant recipients with an history of diabetes.
Transplant Proc. 2013 May;45(4):1497-502. doi: 10.1016/j.transproceed.2012.10.055.
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The impact of early corticosteroid withdrawal on graft survival in liver transplant recipients.早期停用皮质类固醇对肝移植受者移植物存活的影响。
Transplant Proc. 2012 Jun;44(5):1323-8. doi: 10.1016/j.transproceed.2012.01.110.

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Combined Organ Transplantation in Patients with Advanced Liver Disease.联合器官移植治疗晚期肝病患者。
Semin Liver Dis. 2024 Aug;44(3):369-382. doi: 10.1055/s-0044-1788674. Epub 2024 Jul 25.
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Evolutions in Combined Heart-Kidney Transplant.心脏-肾脏联合移植的演变。
Curr Heart Fail Rep. 2024 Apr;21(2):139-146. doi: 10.1007/s11897-024-00646-0. Epub 2024 Jan 17.
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Impact on Waitlist Outcomes from Changes in the Medical Eligibility of Candidates for Simultaneous Liver-Kidney Transplantation Following Implementation of the 2017 Organ Procurement and Transplantation Network/United Network for Organ Sharing Policy in the United States.美国 2017 年器官获取与移植网络/器官共享联合网络政策实施后，候选者同时进行肝肾移植的医学资格变化对候补者结果的影响。
Ann Transplant. 2022 Feb 18;27:e934850. doi: 10.12659/AOT.934850.
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CON: Liver Transplant Alone.反对意见：仅进行肝移植。
Clin Liver Dis (Hoboken). 2021 Jan 13;16(6):272-275. doi: 10.1002/cld.979. eCollection 2020 Dec.

本文引用的文献

1
Lack of Benefit and Potential Harm of Induction Therapy in Simultaneous Liver-Kidney Transplants.肝肾联合移植中诱导治疗的无获益及潜在危害
Liver Transpl. 2019 Mar;25(3):411-424. doi: 10.1002/lt.25390.
2
Glucocorticosteroid-free versus glucocorticosteroid-containing immunosuppression for liver transplanted patients.肝移植患者使用不含糖皮质激素与含糖皮质激素的免疫抑制治疗对比
Cochrane Database Syst Rev. 2018 Apr 9;4(4):CD007606. doi: 10.1002/14651858.CD007606.pub4.
3
OPTN/SRTR 2016 Annual Data Report: Kidney.OPTN/SRTR 2016 年度数据报告：肾脏。
Am J Transplant. 2018 Jan;18 Suppl 1(Suppl 1):18-113. doi: 10.1111/ajt.14557.
4
OPTN/SRTR 2016 Annual Data Report: Liver.OPTN/SRTR 2016 年度数据报告：肝脏。
Am J Transplant. 2018 Jan;18 Suppl 1:172-253. doi: 10.1111/ajt.14559.
5
Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial.兔抗胸腺细胞球蛋白或巴利昔单抗诱导治疗在肾移植后快速撤停激素（Harmony）：一项开放标签、多中心、随机对照试验。
Lancet. 2016 Dec 17;388(10063):3006-3016. doi: 10.1016/S0140-6736(16)32187-0. Epub 2016 Nov 19.
6
Acute Rejection Increases Risk of Graft Failure and Death in Recent Liver Transplant Recipients.急性排斥反应增加近期肝移植受者移植物失功和死亡风险。
Clin Gastroenterol Hepatol. 2017 Apr;15(4):584-593.e2. doi: 10.1016/j.cgh.2016.07.035. Epub 2016 Aug 25.
7
Conversion From Calcineurin to Mammalian Target of Rapamycin Inhibitors in Liver Transplantation: A Meta-Analysis of Randomized Controlled Trials.肝移植中从钙调神经磷酸酶抑制剂转换为雷帕霉素哺乳动物靶点抑制剂：一项随机对照试验的荟萃分析
Transplantation. 2016 Mar;100(3):621-9. doi: 10.1097/TP.0000000000001006.
8
Everolimus with reduced tacrolimus improves renal function in de novo liver transplant recipients: a randomized controlled trial.依维莫司联合低剂量他克莫司治疗肝移植受者：一项随机对照试验。
Am J Transplant. 2012 Nov;12(11):3008-20. doi: 10.1111/j.1600-6143.2012.04212.x. Epub 2012 Aug 6.
9
A prospective, randomized, double-blind, placebo-controlled multicenter trial comparing early (7 day) corticosteroid cessation versus long-term, low-dose corticosteroid therapy.一项前瞻性、随机、双盲、安慰剂对照的多中心试验，比较早期（7天）停用皮质类固醇与长期低剂量皮质类固醇治疗。
Ann Surg. 2008 Oct;248(4):564-77. doi: 10.1097/SLA.0b013e318187d1da.