• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

ALK阳性非小细胞肺癌中酷似脑脓肿的脑转移

Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer.

作者信息

Sakatani Toshio, Kage Hidenori, Takayanagi Shunsaku, Watanabe Kaoru, Hiraishi Yoshihisa, Shinozaki-Ushiku Aya, Tanaka Shota, Ushiku Tetsuo, Saito Nobuhito, Nagase Takahide

机构信息

Department of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

出版信息

Case Rep Oncol Med. 2019 Jun 17;2019:9141870. doi: 10.1155/2019/9141870. eCollection 2019.

DOI:10.1155/2019/9141870
PMID:31316849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6604465/
Abstract

Brain metastasis frequently develops in non-small-cell lung cancer (NSCLC). Here, we report a patient who developed brain metastasis from -positive NSCLC which mimicked brain abscess. He was admitted for suspected obstructive pneumonia nine months after curative lung resection. Head magnetic resonance imaging revealed a cavitary lesion, which was compatible with brain abscess but rare in brain metastasis. However, after treatment with antibiotics, the brain lesion increased in size. Aspiration of the liquid content of the brain lesion revealed cancer cells. When a brain lesion suggestive of abscess develops in a patient with -positive NSCLC, aspiration may be necessary to differentiate metastasis from abscess.

摘要

脑转移在非小细胞肺癌(NSCLC)中经常发生。在此,我们报告一例来自阳性NSCLC的脑转移患者,其表现类似脑脓肿。他在根治性肺切除术后9个月因疑似阻塞性肺炎入院。头部磁共振成像显示一个空洞性病变,这与脑脓肿相符,但在脑转移中罕见。然而,抗生素治疗后,脑病变大小增加。对脑病变的液体内容物进行抽吸发现了癌细胞。当阳性NSCLC患者出现提示脓肿的脑病变时,可能需要进行抽吸以区分转移瘤和脓肿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a1/6604465/38ab291a49e3/CRIONM2019-9141870.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a1/6604465/38ab291a49e3/CRIONM2019-9141870.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a1/6604465/38ab291a49e3/CRIONM2019-9141870.001.jpg

相似文献

1
Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer.ALK阳性非小细胞肺癌中酷似脑脓肿的脑转移
Case Rep Oncol Med. 2019 Jun 17;2019:9141870. doi: 10.1155/2019/9141870. eCollection 2019.
2
Bilateral ovarian metastasis of non-small cell lung cancer with ALK rearrangement.ALK 重排的非小细胞肺癌双侧卵巢转移。
Lung Cancer. 2014 Feb;83(2):302-4. doi: 10.1016/j.lungcan.2013.11.022. Epub 2013 Dec 1.
3
Activity and safety of ceritinib in patients with ALK-rearranged non-small-cell lung cancer (ASCEND-1): updated results from the multicentre, open-label, phase 1 trial.色瑞替尼在间变性淋巴瘤激酶(ALK)重排的非小细胞肺癌患者中的活性与安全性(ASCEND-1):多中心、开放标签、1期试验的更新结果
Lancet Oncol. 2016 Apr;17(4):452-463. doi: 10.1016/S1470-2045(15)00614-2. Epub 2016 Mar 11.
4
Treatment Optimization for Brain Metastasis from Anaplastic Lymphoma Kinase Rearrangement Non-Small-Cell Lung Cancer.治疗间变性淋巴瘤激酶重排非小细胞肺癌脑转移
Oncol Res Treat. 2019;42(11):599-606. doi: 10.1159/000502755. Epub 2019 Sep 17.
5
The Incidence of Brain Metastases in Stage IV ROS1-Rearranged Non-Small Cell Lung Cancer and Rate of Central Nervous System Progression on Crizotinib.ROS1 重排 IV 期非小细胞肺癌脑转移的发生率和克唑替尼治疗下中枢神经系统进展率。
J Thorac Oncol. 2018 Nov;13(11):1717-1726. doi: 10.1016/j.jtho.2018.07.001. Epub 2018 Jul 5.
6
[A Case of Slowly Progressive Brain Metastasis with Minor Bleeding after Removal of and Chemotherapy for Non-Small Cell Lung Cancer].[非小细胞肺癌切除及化疗后发生缓慢进展性脑转移伴少量出血1例]
No Shinkei Geka. 2017 Apr;45(4):339-344. doi: 10.11477/mf.1436203506.
7
De novo cystic brain lesions mimicking neurocysticercosis in ALK-positive lung cancer.ALK阳性肺癌中酷似神经囊尾蚴病的新发脑囊肿性病变
Lung Cancer. 2017 Aug;110:53-55. doi: 10.1016/j.lungcan.2017.06.003. Epub 2017 Jun 12.
8
Computed Tomography Imaging Characteristics of Non-Small-Cell Lung Cancer With Anaplastic Lymphoma Kinase Rearrangements: A Systematic Review and Meta-Analysis.具有间变性淋巴瘤激酶重排的非小细胞肺癌的计算机断层扫描成像特征:系统评价和荟萃分析。
Clin Lung Cancer. 2019 Sep;20(5):339-349. doi: 10.1016/j.cllc.2019.05.006. Epub 2019 May 11.
9
Durable brain response with pulse-dose crizotinib and ceritinib in ALK-positive non-small cell lung cancer compared with brain radiotherapy.与脑放疗相比,脉冲剂量克唑替尼和色瑞替尼对ALK阳性非小细胞肺癌的持久脑反应。
J Clin Neurosci. 2016 Apr;26:46-9. doi: 10.1016/j.jocn.2015.05.068. Epub 2015 Dec 8.
10
Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study.克唑替尼耐药的间变性淋巴瘤激酶(ALK)重排非小细胞肺癌(NSCLC)患者中艾乐替尼针对全身疾病和脑转移的安全性和活性:一项 1/2 期研究剂量探索部分的结果。
Lancet Oncol. 2014 Sep;15(10):1119-28. doi: 10.1016/S1470-2045(14)70362-6. Epub 2014 Aug 18.

引用本文的文献

1
Non-Small Cell Lung Cancer With Brain Metastases and Concomitant Brain Abscesses.伴有脑转移和脑脓肿的非小细胞肺癌
Adv Radiat Oncol. 2024 Nov 2;10(1):101666. doi: 10.1016/j.adro.2024.101666. eCollection 2025 Jan.
2
Comparison of clinical and MRI features of brain metastases between ALK+ and ALK- NSCLC.比较 ALK+ 和 ALK- NSCLC 脑转移的临床和 MRI 特征。
Cancer Med. 2024 Jun;13(11):e7405. doi: 10.1002/cam4.7405.
3
Diffusion-weighted imaging-based radiomics model using automatic machine learning to differentiate cerebral cystic metastases from brain abscesses.

本文引用的文献

1
Hemorrhagic Brain Metastases in a Patient with Anaplastic Lymphoma Kinase (ALK)-Rearranged Invasive Mucinous Adenocarcinoma of the Lung.一名患有间变性淋巴瘤激酶(ALK)重排的侵袭性黏液腺癌的患者发生脑转移出血
Am J Case Rep. 2018 Jan 26;19:99-104. doi: 10.12659/ajcr.906803.
2
De novo cystic brain lesions mimicking neurocysticercosis in ALK-positive lung cancer.ALK阳性肺癌中酷似神经囊尾蚴病的新发脑囊肿性病变
Lung Cancer. 2017 Aug;110:53-55. doi: 10.1016/j.lungcan.2017.06.003. Epub 2017 Jun 12.
3
Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastasis.
基于扩散加权成像的放射组学模型,采用自动机器学习方法,用于区分脑囊性转移瘤和脑脓肿。
J Cancer Res Clin Oncol. 2024 Mar 16;150(3):132. doi: 10.1007/s00432-024-05642-4.
4
Unusual magnetic resonance imaging findings of brain and leptomeningeal metastasis in lung adenocarcinoma: A case report.肺腺癌脑和软脑膜转移的不寻常磁共振成像表现:一例报告。
World J Clin Cases. 2022 Feb 16;10(5):1723-1728. doi: 10.12998/wjcc.v10.i5.1723.
ALK重排的非小细胞肺癌合并脑转移患者的生存延长及预后因素
J Clin Oncol. 2016 Jan 10;34(2):123-9. doi: 10.1200/JCO.2015.62.0138. Epub 2015 Oct 5.
4
Targeting brain metastases in ALK-rearranged non-small-cell lung cancer.针对 ALK 重排非小细胞肺癌的脑转移。
Lancet Oncol. 2015 Oct;16(13):e510-21. doi: 10.1016/S1470-2045(15)00013-3.
5
Brain metastases in patients with EGFR-mutated or ALK-rearranged non-small-cell lung cancers.表皮生长因子受体(EGFR)突变或间变性淋巴瘤激酶(ALK)重排的非小细胞肺癌患者的脑转移
Lung Cancer. 2015 Apr;88(1):108-11. doi: 10.1016/j.lungcan.2015.01.020. Epub 2015 Feb 4.
6
Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study.克唑替尼耐药的间变性淋巴瘤激酶(ALK)重排非小细胞肺癌(NSCLC)患者中艾乐替尼针对全身疾病和脑转移的安全性和活性:一项 1/2 期研究剂量探索部分的结果。
Lancet Oncol. 2014 Sep;15(10):1119-28. doi: 10.1016/S1470-2045(14)70362-6. Epub 2014 Aug 18.
7
Brain metastases. Histology, multiplicity, surgery, and survival.脑转移瘤。组织学、多发性、手术及生存情况。
Cancer. 1996 Oct 15;78(8):1781-8.