哺乳动物肾脏对尿素的主动转运。
Active transport of urea by mammalian kidney.
作者信息
Beyer K H, Gelarden R T
机构信息
Department of Pharmacology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
出版信息
Proc Natl Acad Sci U S A. 1988 Jun;85(11):4030-1. doi: 10.1073/pnas.85.11.4030.
Abstract
With the aid of three basic organic compounds, 2-pyrazinoylguanidine, 3-amino-2-pyrazinoylguanidine, and 3,5-diamino-6-fluoro-2-pyrazinoylguanidine, urea was shown to be secreted by the renal tubules of the dog both from the lumen and into the lumen independent of urine flow.
摘要
借助三种基本有机化合物，即2-吡嗪甲酰胍、3-氨基-2-吡嗪甲酰胍和3,5-二氨基-6-氟-2-吡嗪甲酰胍，研究表明尿素可由犬肾小管从管腔分泌至管腔内外，且与尿流无关。
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'Benemid,' p-(di-n-propylsulfamyl)-benzoic acid; its renal affinity and its elimination.“丙磺舒”，对-（二正丙基氨磺酰基）苯甲酸；其对肾脏的亲和力及其排泄。
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