Division of Adult Reconstruction and Joint Replacement, Hospital for Special Surgery, New York, NY, USA.
Hip Int. 2020 Nov;30(6):725-730. doi: 10.1177/1120700019864867. Epub 2019 Jul 18.
Non-oncologic total femoral replacement (TFR) is utilised as a limb-salvage option in the setting of massive bone loss during revision total hip arthroplasty (THA) and total knee arthroplasty (TKA). However, complication rates, including infection and reoperation, remain a concern.
In this study, 16 consecutive TFRs from a single institution with an average clinical follow-up of 4 years were retrospectively reviewed. Indications for TFR, previous surgeries, implants used, complications, reoperations, and ambulatory status at final follow-up were recorded.
The reoperation rate was 50%, and those patients averaged 2 additional surgeries after TFR. The most common reason for reoperation was infection with a 33% incidence of a new periprosthetic infection and an overall infection rate of 44% (7/16). 6/7 were managed with irrigation and debridement and implant retention. Dual-mobility and constrained acetabular liners were used consistently, and no patient experienced a subsequent dislocation. At final follow-up, 81% were ambulatory but only 2 patients (13%) could walk without an assistive device. No patient required amputation.
While TFR achieved limb salvage in all patients with fair clinical outcomes, patients were at high risk for new or persistent infection and reoperation. Dual-mobility and constrained acetabular liners were effective in preventing dislocation is this cohort.
在翻修全髋关节置换术(THA)和全膝关节置换术(TKA)时,由于大量骨丢失,非肿瘤性全股骨置换(TFR)可用作保肢选择。然而,包括感染和再次手术在内的并发症发生率仍然令人担忧。
本研究回顾性分析了来自一家单机构的 16 例连续 TFR,平均临床随访时间为 4 年。记录 TFR 的适应证、既往手术、使用的植入物、并发症、再次手术和最终随访时的步行状态。
再次手术率为 50%,这些患者平均在 TFR 后进行了 2 次额外手术。再次手术的最常见原因是感染,新发假体周围感染的发生率为 33%,总感染率为 44%(7/16)。7 例中的 6 例采用冲洗和清创及保留植入物治疗。双动和约束性髋臼衬垫一直被使用,没有患者发生随后的脱位。最终随访时,81%的患者可活动,但只有 2 例(13%)无需辅助设备即可行走。没有患者需要截肢。
尽管 TFR 使所有患者实现了肢体挽救,且临床结果尚可,但患者存在新发或持续感染和再次手术的高风险。在本队列中,双动和约束性髋臼衬垫可有效预防脱位。