Department of Neurosurgery, Wei Fang People's Hospital , Weifang , China.
Department of Pathology, Weifang Medical University , Weifang , China.
Int J Neurosci. 2019 Dec;129(12):1179-1182. doi: 10.1080/00207454.2019.1645139. Epub 2019 Jul 25.
Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy that leads to sensory, motor and autonomic symptoms. We report a 26-year-old female patient with GBS revealed headache and limbs weakness. Treatment with gammaglobulin and corticosteroids led to a rapid improvement of muscle strength. However, she developed more severe headache and increased intracranial pressure which can be relieved by ventricular drainage during recovery period of GBS. Headache and increased intracranial pressure in GBS was relatively rare. This report reviews some literatures about this disorder and analyses possible pathophysiological mechanisms of intracranial hypertension in GBS. We should pay attention to patients who exhibit atypical presentations.
格林-巴利综合征（GBS）是一种急性炎症性脱髓鞘性多发性神经病，可导致感觉、运动和自主症状。我们报告了一例 26 岁女性 GBS 患者，表现为头痛和四肢无力。使用丙种球蛋白和皮质类固醇治疗后，肌力迅速改善。然而，她在 GBS 的恢复期出现了更严重的头痛和颅内压增高，脑室引流可缓解头痛和颅内压增高。GBS 中的头痛和颅内压增高相对少见。本报告回顾了一些关于这种疾病的文献，并分析了 GBS 中颅内压升高的可能病理生理机制。我们应该注意表现出非典型表现的患者。
