Department of Medicine,Division of Neurology,University of Alberta,Edmonton,Alberta,Canada.
Can J Neurol Sci. 2018 Mar;45(2):240-242. doi: 10.1017/cjn.2017.247.
Headache is an uncommon symptom in Guillain-Barré syndrome (GBS). We review four clinical settings related to GBS in which headache may be present. We focus on pathophysiological explanations, alerting the clinician to further potential investigations and treatment. Most reports of headache in GBS occur in the context of the posterior reversible encephalopathy syndrome, an increasingly recognized dysautonomia-related GBS complication. Less frequent is headache in the setting of increased intracranial pressure and papilledema (secondary intracranial hypertension), Miller Fisher syndrome, and cerebral venous sinus thrombosis. Rarely, headache can occur secondary to aseptic meningitis from IVIg use.
头痛是吉兰-巴雷综合征（GBS）中不常见的症状。我们回顾了与 GBS 相关的四个临床环境，其中可能存在头痛。我们专注于病理生理学解释，提醒临床医生进一步进行潜在的调查和治疗。GBS 中头痛的大多数报告发生在后可逆性脑病综合征（一种越来越被认识到的与自主神经功能障碍相关的 GBS 并发症）的背景下。不太常见的是，头痛发生在颅内压增高和视盘水肿（继发性颅内高压）、米勒-费舍尔综合征和脑静脉窦血栓形成的情况下。头痛很少发生在 IVIg 使用引起的无菌性脑膜炎的情况下。
