Vivent, Rosmalen and Livio, Enschede, The Netherlands.
Department of Primary and Community Care, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
J Adv Nurs. 2019 Dec;75(12):3715-3725. doi: 10.1111/jan.14156. Epub 2019 Aug 5.
Establishing the prevalence of neuropsychiatric symptoms (NPS), quality of life and psychotropic drug use in people aged ≤65 years with acquired brain injury in nursing homes.
Cross-sectional, observational study among patients aged 18-≤65 years with acquired brain injury admitted to special care units in Dutch nursing homes.
According to the Committee on Research Involving Human Subjects in January 2017 this study did not require ethics approval. Nursing homes will be recruited through the national acquired brain injury expertise network for patients with severe brain injury, the regional brain injury teams and by searching the internet. Patient characteristics will be collected through digital questionnaires. Neuropsychiatric symptoms will be assessed with the NeuroPsychiatric Inventory-Nursing Home version, the Cohen-Mansfield Agitation Inventory and the St. Andrews Sexual Behaviour Assessment; cognition with the Mini-Mental State Examination, quality of life with the Quality of Life after Brain Injury Overall Scale and activities of daily living with the Disability Rating Scale. Medication will be retrieved from the electronic prescription system. Data collection commenced in 2017 and will be followed by data analysis in 2019. Reporting will be completed in 2020.
Little is known about NPS among patients with acquired brain injury in nursing homes. In patients up to the age of 65 years, only six studies were found on prevalence rates of NPS.
Patients with severe acquired brain injury experience lifelong consequences, that have a high impact on them and their environment. Although there is increasing attention for the survival of this vulnerable group of patients, it is also important to enlarge awareness on long-term consequences, specifically the NPS, quality of life and psychotropic drug use in acquired brain injury. Insight into the magnitude of these issues is necessary to achieve appropriate care for these patients.
调查≤65 岁在养老院中患有后天性脑损伤患者的神经精神症状（NPS）、生活质量和精神药物使用情况的流行率。
在荷兰养老院的特殊护理病房中，对年龄在 18 至≤65 岁之间患有后天性脑损伤的患者进行横断面、观察性研究。
根据 2017 年 1 月的人体研究委员会，这项研究不需要伦理批准。将通过国家严重脑损伤专业知识网络、区域脑损伤团队以及互联网搜索来招募养老院。将通过数字问卷收集患者特征。使用神经精神病学入院评估表（NeuroPsychiatric Inventory-Nursing Home version）、科恩-曼斯菲尔德激越量表（Cohen-Mansfield Agitation Inventory）和圣安德鲁斯性行为评估量表（St. Andrews Sexual Behaviour Assessment）评估神经精神症状；使用简易精神状态检查（Mini-Mental State Examination）评估认知功能；使用生活质量后脑损伤综合量表（Quality of Life after Brain Injury Overall Scale）评估生活质量；使用残疾评定量表（Disability Rating Scale）评估日常生活活动能力。从电子处方系统中检索药物。数据收集于 2017 年开始，2019 年进行数据分析，2020 年完成报告。
养老院中患有后天性脑损伤的患者的 NPS 情况知之甚少。在 65 岁以下的患者中，仅发现了六项关于 NPS 患病率的研究。
患有严重后天性脑损伤的患者会经历终身后果，这对他们及其环境都有很大的影响。尽管人们越来越关注这一脆弱患者群体的生存问题，但扩大对后天性脑损伤患者的长期后果（特别是 NPS、生活质量和精神药物使用）的认识也很重要。了解这些问题的严重程度对于为这些患者提供适当的护理是必要的。
