Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia.
Department of Pediatrics, Division of Hematology/Oncology, Emory University School of Medicine, Atlanta, Georgia.
Pediatr Blood Cancer. 2019 Oct;66(10):e27921. doi: 10.1002/pbc.27921. Epub 2019 Jul 18.
Blood transfusions are indicated for some acute complications of sickle cell disease (SCD). To characterize the SCD population at increased risk of transfusion-associated complications, Georgia hospital discharge data were used to estimate the frequency of intermittent transfusions and the proportion of patients receiving them at multiple institutions. Ten years of data (2007-2016) showed almost 19% of patients with SCD (1585/8529) received transfusions at more than one hospital. The likelihood of multisite transfusions increased from ages 18 through 40 and with the number of transfusions received. The results support the need to track and share transfusion histories in order to reduce complication risks.
输血用于治疗镰状细胞病（SCD）的一些急性并发症。为了描述具有输血相关并发症高风险的 SCD 人群，利用佐治亚州住院数据来估计间歇性输血的频率以及在多家机构接受输血的患者比例。10 年的数据（2007-2016 年）显示，近 19%的 SCD 患者（1585/8529）在多家医院接受输血。从 18 岁到 40 岁，以及接受输血的次数，多部位输血的可能性增加。结果支持需要跟踪和共享输血史，以降低并发症风险。
