Brookmeyer Kathryn A, Haderxhanaj Laura T, Hogben Matthew, Leichliter Jami
Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of STD Prevention, United States of America.
Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of STD Prevention, United States of America.
Prev Med. 2019 Sep;126:105779. doi: 10.1016/j.ypmed.2019.105779. Epub 2019 Jul 15.
Opioid use and the rising case reports of STDs represent co-occurring epidemics; research indicates that persons who inject drugs (PWID) may be at increased risk for acquiring STDs. We use the National Survey of Family Growth (NSFG, 2011-2015) to examine the prevalence of risky sexual behaviors and STD diagnoses among PWID. We describe demographic characteristics, sexual behaviors, and self-reported STD diagnoses of sexually active women and men, separately, by whether they had ever engaged in injection-related behaviors (age 15-44; N = 9006 women, N = 7210 men). Results indicate that in 2011-15, 1.4% of women and 2.6% of men reported ever engaging in injection-related behaviors. Examining the full logistic regression models indicate that for women, sex with a PWID in the past 12 months (AOR = 5.8, 95% CI: 2.9, 11.7), exchanging money/drugs for sex in the past 12 months (AOR = 3.6, 95% CI: 1.2, 10.9), chlamydia and/or gonorrhea diagnosis in the past 12 months (AOR = 2.6, 95% CI: 1.2, 5.3), ever having a syphilis diagnosis (AOR = 8.5, 95% CI: 3.1, 23.4), and ever having a herpes diagnosis (AOR = 3.3, 95% CI: 1.0, 10.3) were associated with increased odds of engaging in injection-related behaviors. For men, sex with a PWID in the past 12 months (AOR = 10.9, 95% CI: 4.3, 27.7), ever being diagnosed with syphilis (AOR = 5.8, 95% CI: 1.8, 18.0), and ever being diagnosed with herpes (AOR = 2.7, 95% CI: 1.0, 7.1) were significantly associated with increased odds of engaging in injection-related behaviors. Future research may examine critical intervention points, including co-occurring factors in both STD acquisition and injection drug use.
阿片类药物的使用以及性传播疾病病例报告的不断增加代表了同时出现的流行病；研究表明，注射毒品者感染性传播疾病的风险可能更高。我们利用全国家庭成长调查（NSFG，2011 - 2015年）来研究注射毒品者中危险性行为和性传播疾病诊断的流行情况。我们分别描述了性活跃的女性和男性的人口统计学特征、性行为以及自我报告的性传播疾病诊断情况，根据他们是否曾经有过与注射相关的行为（年龄15 - 44岁；女性N = 9006人，男性N = 7210人）。结果表明，在2011 - 2015年期间，1.4%的女性和2.6%的男性报告曾经有过与注射相关的行为。对完整逻辑回归模型的分析表明，对于女性来说，在过去12个月内与注射毒品者发生性行为（比值比[AOR]=5.8，95%置信区间[CI]：2.9，11.7）、在过去12个月内用金钱/毒品换取性行为（AOR = 3.6，95% CI：1.2，10.9）、在过去12个月内衣原体和/或淋病诊断（AOR = 2.6，95% CI：1.2，5.3）、曾经有过梅毒诊断（AOR = 8.5，95% CI：3.1，23.4）以及曾经有过疱疹诊断（AOR = 3.3，95% CI：1.0，10.3）与从事与注射相关行为的几率增加有关。对于男性来说，在过去12个月内与注射毒品者发生性行为（AOR = 10.9，95% CI：4.3，27.7）、曾经被诊断出患有梅毒（AOR = 5.8，95% CI：1.8，18.0）以及曾经被诊断出患有疱疹（AOR = 2.7，95% CI：1.0，7.1）与从事与注射相关行为的几率显著增加有关。未来的研究可以考察关键干预点，包括性传播疾病感染和注射毒品使用中的共同因素。
