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使用衰弱指数评估日本老年人衰弱的流行率、相关因素以及衰弱工具间的一致性。

Frailty prevalence using Frailty Index, associated factors and level of agreement among frailty tools in a cohort of Japanese older adults.

机构信息

Adelaide Geriatrics Training and Research with Aged Care (G-TRAC Centre), Discipline of Medicine, Adelaide Medical School, University of Adelaide, 61 Silkes Rd., Paradise, South Australia, 5075, Australia; National Health and Medical Research Council Centre of Research Excellence Frailty and Healthy Ageing, University of Adelaide, South Australia, 5000, Australia; Department of Community Health and Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa Ward, Nagoya-shi, Aichi Prefecture, 466-8560, Japan.

Adelaide Geriatrics Training and Research with Aged Care (G-TRAC Centre), Discipline of Medicine, Adelaide Medical School, University of Adelaide, 61 Silkes Rd., Paradise, South Australia, 5075, Australia; National Health and Medical Research Council Centre of Research Excellence Frailty and Healthy Ageing, University of Adelaide, South Australia, 5000, Australia.

出版信息

Arch Gerontol Geriatr. 2019 Sep-Oct;84:103908. doi: 10.1016/j.archger.2019.103908. Epub 2019 Jul 8.

Abstract

UNLABELLED

Frailty prevalence defined by the deficit accumulation model (Frailty Index) has limited exploration in a Japanese population. The objective of this paper is to investigate the prevalence of frailty by Frailty Index among a cohort of healthy Japanese older adults, define risk factors associated with pre-frailty and frailty status and evaluate Frailty Index's agreement with Frailty Phenotype and Kihon checklist.

METHODS

Data from 673 participants of the 2014 wave of the Nagoya Longitudinal Study - Healthy Elderly were used. Annual assessments include investigation of mood, memory, health status, nutrition, physical performance and oral health. The Frailty Index was compared to Frailty Phenotype and Kihon Checklist, and factors associated to Frailty Index were investigated through univariate and multivariate logistic regression.

RESULTS

Frailty prevalence was 13.5% (n = 91) by Frailty Index, 1.5% (n = 10) by Frailty Phenotype and 4% (n = 27) by Kihon Checklist. Although the correlations between the three scales were moderate to high, the agreement between the scales was poor. In terms of risk factors, age, polypharmacy and physical activity level were associated with being pre-frail and frail. Having a higher waist circumference was associated with being pre-frail, and lower handgrip strength and lower walking speed were associated with being frail.

CONCLUSIONS

The Frailty Index showed similar metrics and agreement comparable to findings of previous studies, and was able to identify a higher number of individuals who were pre-frail and frail. Age, polypharmacy, physical activity, waking speed and waist circumference were associated with pre-frailty and frailty by frailty index.

摘要

背景:基于衰弱积累模型(衰弱指数)定义的衰弱流行率在日本人群中鲜有探索。本研究旨在调查健康的日本老年人队列中衰弱指数定义的衰弱流行率,确定与虚弱前期和衰弱状态相关的危险因素,并评估衰弱指数与衰弱表型和健康问卷的一致性。

方法:本研究使用了 2014 年名古屋纵向研究-健康老年人队列的 673 名参与者的数据。每年的评估包括情绪、记忆、健康状况、营养、身体表现和口腔健康的调查。衰弱指数与衰弱表型和健康问卷进行了比较,并通过单变量和多变量逻辑回归分析了与衰弱指数相关的因素。

结果:根据衰弱指数,衰弱的流行率为 13.5%(n=91),根据衰弱表型为 1.5%(n=10),根据健康问卷为 4%(n=27)。尽管这三种量表之间的相关性为中度至高度,但量表之间的一致性较差。在危险因素方面,年龄、多药治疗和身体活动水平与虚弱前期和衰弱有关。较高的腰围与虚弱前期有关,而较低的握力和较慢的步行速度与衰弱有关。

结论:衰弱指数表现出与先前研究相似的指标和可比的一致性,并能够识别更多的虚弱前期和衰弱个体。年龄、多药治疗、身体活动、步行速度和腰围与衰弱指数定义的虚弱前期和衰弱有关。

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