Mareschal Julie, Achamrah Najate, Norman Kristina, Genton Laurence
Clinical Nutrition, Geneva University Hospitals, 1205 Geneva, Switzerland.
Department of Clinical Nutrition, Rouen University Hospital, Normandie University, 76000 Rouen, France.
J Clin Med. 2019 Jul 17;8(7):1040. doi: 10.3390/jcm8071040.
Malnutrition results from a reduction of food intake or an alteration of nutrient assimilation and leads to decreased lean mass. Strong evidence shows that malnutrition associated with loss of muscle mass negatively impacts clinical outcomes. The preservation or improvement of muscle mass represents a challenge. This review aims to (1) describe current methods to assess muscle mass in clinical practice, (2) describe the associations between muscle mass and clinical outcomes, and (3) describe the impact of interventions aiming at increasing muscle mass on clinical outcomes. It highlights the importance of assessing muscle mass as part of the screening and the follow-up of malnutrition in clinical practice.
营养不良是由食物摄入量减少或营养物质同化改变引起的,会导致瘦体重下降。有力证据表明,与肌肉量减少相关的营养不良会对临床结局产生负面影响。维持或增加肌肉量是一项挑战。本综述旨在:(1)描述临床实践中评估肌肉量的现有方法;(2)描述肌肉量与临床结局之间的关联;(3)描述旨在增加肌肉量的干预措施对临床结局的影响。它强调了在临床实践中评估肌肉量作为营养不良筛查和随访一部分的重要性。