School of Medicine, University of the West Indies, St. Augustine Campus, Trinidad and Tobago.
Department of Clinical Medical Sciences, University of the West Indies, St. Augustine Campus, Trinidad and Tobago.
BMC Health Serv Res. 2019 Jul 18;19(1):501. doi: 10.1186/s12913-019-4344-2.
Cardiovascular disease remains the most common cause of death. However, effective and timely secondary care contributes to improved quality of life, decreased morbidity and mortality. This study analyzed the medical care of patients in a resource limiting country with a first presentation of acute myocardial infarction (AMI).
A cross-sectional retrospective study was conducted on first time AMI patients admitted between March 1st 2011 and March 31st 2015 to the only tertiary public hospital in a resource limiting country, Trinidad. Relevant data were obtained from all confirmed AMI patients.
Data were obtained from 1106 AMI patients who were predominantly male and of Indo Trinidadian descent. Emergency treatment included aspirin (97.2%), clopidogrel (97.2%), heparin (81.3%) and thrombolysis (70.5% of 505 patients with ST elevation MI), but none of the patients had primary angioplasty. Thrombolysis was higher among younger patients and in men. There were no differences in age, sex, and ethnicity in all other treatments. Of the 360 patients with recorded times, 41.1% arrived at the hospital within 4 h. The proportion of patients receiving thrombolysis (door to needle time) within 30 min was 57.5%. In-patient treatment medication included: aspirin (87.1%), clopidogrel (87.2%), beta blockers (76.5%), ACEI (72.9%), heparin (80.6%), and simvastatin (82.5%). Documentation of risk stratification, use of angiogram and surgical intervention, initiation of cardiac rehabilitation (CR), and information on behavioral changes were rare. Electrocardiogram (ECG) and cardiac enzyme tests were universally performed, while echocardiogram was performed in 57.1% of patients and exercise stress test was performed occasionally. Discharge treatment was limited to medication and referrals for investigations. Few patients were given lifestyle and activity advice and referred for CR. The in-hospital death rate was 6.5%. There was a significantly higher relative risk of in-hospital death for non-use of aspirin, clopidogrel, simvastatin, beta blockers, and heparin, but not ACE inhibitors and nitrates.
Medication usage was high among AMI patients. However, there was very minimal use of non-pharmacological measures. No differences were found in prescribed medication by age, sex, or ethnicity, with the exception of thrombolysis.
心血管疾病仍然是最常见的死亡原因。然而,有效的、及时的二级护理有助于提高生活质量,降低发病率和死亡率。本研究分析了资源有限国家首次出现急性心肌梗死(AMI)患者的医疗护理情况。
对 2011 年 3 月 1 日至 2015 年 3 月 31 日期间在资源有限国家的唯一一家三级公立医院收治的首次确诊为急性心肌梗死的患者进行了一项横断面回顾性研究。从所有确诊的急性心肌梗死患者中获得了相关数据。
共获得 1106 例急性心肌梗死患者的数据,这些患者主要为男性,且大多为印度裔特立尼达人。急救治疗包括阿司匹林(97.2%)、氯吡格雷(97.2%)、肝素(81.3%)和溶栓治疗(505 例 ST 段抬高型心肌梗死患者中有 70.5%接受了溶栓治疗),但没有患者接受直接经皮冠状动脉介入治疗。年轻患者和男性患者接受溶栓治疗的比例更高。在其他治疗方面,年龄、性别和种族之间没有差异。在有记录时间的 360 名患者中,41.1%在 4 小时内到达医院。在 30 分钟内接受溶栓治疗(从进医院门到开始溶栓的时间)的患者比例为 57.5%。住院治疗药物包括:阿司匹林(87.1%)、氯吡格雷(87.2%)、β受体阻滞剂(76.5%)、血管紧张素转换酶抑制剂(72.9%)、肝素(80.6%)和辛伐他汀(82.5%)。风险分层、血管造影和手术干预、心脏康复(CR)的启动以及行为改变的信息记录很少。普遍进行了心电图(ECG)和心肌酶检测,而超声心动图在 57.1%的患者中进行,运动负荷试验偶尔进行。出院治疗仅限于药物治疗和检查转诊。很少有患者获得生活方式和活动建议,并被转诊接受 CR。住院死亡率为 6.5%。未使用阿司匹林、氯吡格雷、辛伐他汀、β受体阻滞剂和肝素的患者,其住院死亡的相对风险显著增加,但血管紧张素转换酶抑制剂和硝酸盐除外。
急性心肌梗死患者的药物使用率较高。然而,非药物治疗措施的使用非常有限。除溶栓治疗外,年龄、性别或种族之间在处方药物方面没有差异。