Departamento de Química Analítica, Instituto Universitario de Investigación en Química Fina y Nanoquímica IUNAN, Universidad de Córdoba, Campus de Rabanales, Edificio Marie Curie, E-14071, Córdoba, Spain.
Departamento de Química Analítica, Instituto Universitario de Investigación en Química Fina y Nanoquímica IUNAN, Universidad de Córdoba, Campus de Rabanales, Edificio Marie Curie, E-14071, Córdoba, Spain.
J Chromatogr A. 2019 Nov 22;1606:360359. doi: 10.1016/j.chroma.2019.07.013. Epub 2019 Jul 12.
A portable device that integrates sampling and extraction is proposed in this work. The unit is fabricated using commercial and standardized elements which guarantees the construction reproducibility. Also, it is simple to be mounted and on-site deployed making possible the multi-site sampling. The device uses a commercial nylon membrane as extraction phase for the isolation of the target compounds, but it can be adapted to other flat sorptive phases thus expanding the applicability. Once mounted, the unit is stirred into the sample by means of a portable drill enhancing in that way the diffusion of the target analyte towards the extraction phase. The hydrodynamic behavior and the design have been optimized and the device has been finally used for the extraction benzophenones from swimming pool samples. These endocrine disruptive compounds are determined by liquid chromatography tandem mass spectrometry (LC-MS/MS) at concentrations as low as 0.1 μg/L with precision, expressed as relative standard deviation, better than 9.9%. The accuracy, calculated as relative recovery, was in the range from 74 to 111 % thus being considered appropriate.
本工作提出了一种集成采样和提取的便携式设备。该单元采用商业和标准化元件制造，可保证构建的可重复性。此外，它易于安装和现场部署，可实现多点采样。该设备使用商业尼龙膜作为萃取相，用于分离目标化合物，但它可以适应其他扁平吸附相，从而扩大其适用性。一旦安装好，该单元就可以通过便携式钻头搅拌到样品中，从而增强目标分析物向萃取相的扩散。对其流体动力学行为和设计进行了优化，最终该设备用于从游泳池水样中萃取二苯甲酮。这些内分泌干扰化合物通过液相色谱串联质谱法（LC-MS/MS）在低至 0.1μg/L 的浓度下进行测定，其精密度（表示为相对标准偏差）优于 9.9%。准确度（以相对回收率计算）在 74%至 111%的范围内，因此被认为是合适的。
