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[糖尿病患者突发性感音神经性听力损失的全身及局部治疗方案]

[Systemic and local therapy options for sudden sensorineural hearing loss in diabetics].

作者信息

Leggewie B, Zimmermann A, Strieth S, Gouveris H

机构信息

Hals-Nasen-Ohrenklinik und Poliklinik, Universitätsmedizin Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland.

I. Medizinische Klinik und Poliklinik, Universitätsmedizin Mainz, Mainz, Deutschland.

出版信息

HNO. 2019 Aug;67(8):639-648. doi: 10.1007/s00106-019-0704-9.

Abstract

Sudden sensorineural hearing loss is not an emergency, but an urgency. Depending on severity, the disease may have a major impact on quality of life. Gold standard in Germany is a systemic, high-dosage glucocorticoid therapy. During oral or intravenous therapy with glucocorticoids, systemic side effects may occur. Especially in diabetics, this therapy may cause acute prominent disorders in glucose metabolism and therefore may be contraindicated. An alternative therapeutic option is intratympanic injection of steroids into the middle ear. Hereby the systemic side effects are absent and only local otologic complications may occasionally occur.

摘要

突发性感音神经性听力损失并非急症,而是一种紧急情况。根据严重程度,该病可能对生活质量产生重大影响。在德国,金标准治疗方法是全身性高剂量糖皮质激素疗法。在口服或静脉注射糖皮质激素治疗期间,可能会出现全身性副作用。尤其是糖尿病患者,这种治疗可能会导致糖代谢急性显著紊乱,因此可能是禁忌的。另一种治疗选择是向中耳内鼓室内注射类固醇。由此可避免全身性副作用,仅偶尔可能出现局部耳部并发症。

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