Gulati Amit, Mathew Cinosh, Calton Rajneesh
Senior ResidentChristian Medical College and Hospital, Ludhiana, Punjab.
Associate Professor,Christian Medical College and Hospital, Ludhiana, Punjab.
J Assoc Physicians India. 2018 Sep;66(9):58-61.
Young presentation of acute coronary syndrome (ACS) has been poorly described in literature. We hereby evaluate patients younger than 30 years.
In this prospective study we enrolled 1377 patients who underwent coronary angiography for symptoms concerning for acute coronary syndrome over a period of one year.
Male predominance (100%) was seen among the young patients (less than 30 years) with most common presentation being chest pain. Incidence of ST elevation myocardial infarction (STEMI) was significantly higher (75%) than non-ST elevation myocardial infarction/ unstable angina (NSTEMI/UA). Most common associated risk factor was current smoking (41.6%). As compared to elderly, young patients were seen to have better outcome with percutaneous coronary interventions (PCI) and thrombolysis.
Very young <30 years suffer from ischemia too and may differ in presentation, risk factors and outcome as compared to old. Primary prevention of avoidable risk factors should be aggressively promoted among young.
急性冠状动脉综合征(ACS)在年轻患者中的表现鲜有文献描述。我们在此对30岁以下的患者进行评估。
在这项前瞻性研究中,我们纳入了1377例在一年时间内因疑似急性冠状动脉综合征症状而接受冠状动脉造影的患者。
年轻患者(小于30岁)中男性占主导(100%),最常见的表现为胸痛。ST段抬高型心肌梗死(STEMI)的发生率(75%)显著高于非ST段抬高型心肌梗死/不稳定型心绞痛(NSTEMI/UA)。最常见的相关危险因素是当前吸烟(41.6%)。与老年患者相比,年轻患者接受经皮冠状动脉介入治疗(PCI)和溶栓治疗的预后更好。
30岁以下的极年轻患者也会发生缺血,与老年患者相比,其表现、危险因素和预后可能有所不同。应积极在年轻人中推广对可避免危险因素的一级预防。