Tatarintseva Z G, Kosmacheva E D, Raff S A, Kruchinova S V, Porkhanov V A
Research Institute - Regional Clinical Hospital № 1 named after prof. S. V. Ochapovsky.
Kardiologiia. 2019 Jul 18;59(7):19-25. doi: 10.18087/cardio.2019.7.2503.
to elucidate risk factors of development of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS), and to assess of patient's adherence to oral anticoagulant therapy (OAT) during 12 months after ACS episode according to the data of the Total ACS Registry for the Krasnodar Territory.
In this retrospective analysis we used Registry data on patients with ACS and concomitant AF, consecutively admitted to cardiological departments of the S.V. Ochapovsky Territorial Clinical Hospital from 20/11/2015 to 20/02/18. Number of patients in the analyzed group was 201 (52 with AF which first appeared in connection with the index ACS). Survivors after hospital discharge were contacted by telephone and at planned visits. The analysis included assessment of rates of the following outcomes: inhospital death, hemorrhagic and thromboembolic complications, prognostic efficacy of the CRISADE and HAS BLED scores, and expediency of prescription to patients with ACS and concomitant first AF episode of prolonged OAT after hospital discharge.
Demographic and anamnestic data of patients with the first AF attack at the background of ACS were like those of patients with other types of AF. This group of patients was characterized by more severe course of the disease, but this produced no impact on inhospital mortality and rate of complications, as well as on mortality for 12 months after hospital discharge.
The results of this analysis are important for understanding distinctive characteristics of patients with AF first developed during ACS.
根据克拉斯诺达尔地区急性冠状动脉综合征（ACS）总登记处的数据，阐明ACS患者发生心房颤动（AF）的危险因素，并评估ACS发作后12个月内患者口服抗凝治疗（OAT）的依从性。
在这项回顾性分析中，我们使用了2015年11月20日至2018年2月20日期间连续入住S.V.奥恰波夫斯基地区临床医院心内科的ACS合并AF患者的登记数据。分析组患者人数为201例（52例AF首次出现与索引ACS相关）。出院后的幸存者通过电话和计划访视进行联系。分析包括评估以下结局的发生率：住院死亡、出血和血栓栓塞并发症、CRISADE和HAS BLED评分的预后疗效，以及出院后对ACS合并首次AF发作患者延长OAT处方的适宜性。
ACS背景下首次发生AF的患者的人口统计学和既往史数据与其他类型AF患者相似。这组患者的疾病进程更为严重，但这对住院死亡率、并发症发生率以及出院后12个月的死亡率均无影响。
该分析结果对于了解ACS期间首次发生AF的患者的独特特征具有重要意义。
