重新审视肠道微生物群及其对人类健康和疾病的影响。
Revisit gut microbiota and its impact on human health and disease.
机构信息
College of Food Science, Shenyang Agricultural University, Shenyang 110866, PR China.
Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore 117597, Singapore.
出版信息
J Food Drug Anal. 2019 Jul;27(3):623-631. doi: 10.1016/j.jfda.2018.12.012. Epub 2019 Feb 1.
Abstract
Trillions of microbes have evolved with and continue to live on human beings. With the rapid advances in tools and technology in recent years, new knowledge and insight in cross-talk between the microbes and their hosts have gained. It is the aim of this work to critically review and summarize recent literature reports on the role of microbiota and mechanisms involved in the progress and development of major human diseases, which include obesity, hypertension, cardiovascular disease, diabetes, cancer, Inflammatory Bowel Disease (IBD), gout, depression and arthritis, as well as infant health and longevity.
摘要
数以万亿计的微生物与人类共生，并继续在人类体内生存。近年来，工具和技术的快速进步，使人们对微生物与其宿主之间的相互作用有了新的认识。这项工作的目的是批判性地回顾和总结近年来关于微生物群在肥胖、高血压、心血管疾病、糖尿病、癌症、炎症性肠病 (IBD)、痛风、抑郁和关节炎等主要人类疾病的进展和发展中所起的作用及其相关机制的文献报告，以及婴儿健康和长寿方面的作用。
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