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腓骨游离皮瓣头颈部重建中的虚拟手术规划:系统评价和荟萃分析。

Virtual surgical planning in fibula free flap head and neck reconstruction: A systematic review and meta-analysis.

机构信息

Department of Plastic & Reconstructive Surgery, The Royal Melbourne Hospital, 300 Grattan St, Parkville VIC 3050, Australia.

Department of Plastic & Reconstructive Surgery, The Royal Melbourne Hospital, 300 Grattan St, Parkville VIC 3050, Australia.

出版信息

J Plast Reconstr Aesthet Surg. 2019 Sep;72(9):1465-1477. doi: 10.1016/j.bjps.2019.06.013. Epub 2019 Jul 2.

Abstract

BACKGROUND

The traditional approach to head and neck reconstruction is considered challenging, requiring a subjective assessment of an often-complex defect followed by careful modelling of a bony flap to match this. The introduction of Virtual Surgical Planning (VSP) has provided the surgeon with a means to increase efficiency, precision and overall patient outcomes. This study aims to compare VSP and traditional head and neck reconstructions utilising fibula free flaps with regards surgical efficiency and patient outcomes.

METHODS

A systematic search of the PubMed and Medline databases was performed from the date of their inception through to August 2018 to evaluate and compare VSP and non-VSP cohorts in the context of fibula free flap head and neck reconstruction. Primary comparative outcomes included operative and ischaemic time, with secondary outcomes including complications rates, measures of accuracy and financial benefits.

RESULTS

One hundred and fifty-three articles were identified. Twenty-three articles were included in the review, comprising a total of 713 patients. VSP was associated with significantly decreased intraoperative time (Standardised Mean Difference -1.01; 95% CI -1.23 to 0.80; p = 0.000) and ischaemic time (Standardised Mean Difference -1.55; 95% CI -1.87 to -1.23, p = 0.002). VSP was also associated with reduced orthognathic deviation from an ideal outcome when compared to conventional techniques. No statistically significant differences in complication rates between conventional and VSP techniques were identified.

CONCLUSION

The results of this meta-analysis suggests that VSP confers significant benefits with respect to improved orthognathic accuracy, ischaemic times and intraoperative times without any significant increase in complications. Recommendations for ongoing research are suggested.

摘要

背景

传统的头颈部重建方法被认为具有挑战性,需要对复杂的缺损进行主观评估,然后仔细设计骨瓣以匹配这种缺损。虚拟手术规划(VSP)的引入为外科医生提供了一种提高效率、精度和整体患者治疗效果的手段。本研究旨在比较 VSP 和传统头颈部重建技术,利用游离腓骨皮瓣,评估手术效率和患者治疗效果。

方法

系统检索 PubMed 和 Medline 数据库,从建库日期至 2018 年 8 月,评估和比较 VSP 和非 VSP 队列在游离腓骨皮瓣头颈部重建中的应用。主要比较结果包括手术时间和缺血时间,次要结果包括并发症发生率、准确性评估和经济收益。

结果

共检索到 153 篇文献,23 篇文献纳入本研究,共纳入 713 例患者。VSP 组术中时间明显缩短(标准化均数差 -1.01;95%可信区间 -1.23 至 0.80;p=0.000),缺血时间也明显缩短(标准化均数差 -1.55;95%可信区间 -1.87 至 -1.23;p=0.002)。与传统技术相比,VSP 还可降低术后颌骨畸形的发生率。VSP 组和传统组的并发症发生率无统计学差异。

结论

本荟萃分析结果表明,VSP 可显著提高颌骨畸形的准确性,降低缺血时间和手术时间,且不会增加并发症发生率。建议开展进一步的研究。

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