全鼻切除术治疗鼻癌。
Total rhinectomy for nasal carcinomas.
机构信息
Hospital Ana Nery, Departamento de Cirurgia de Cabeça e Pescoço, Santa Cruz do Sul, RS, Brazil.
Hospital Ana Nery, Departamento de Cirurgia de Cabeça e Pescoço, Santa Cruz do Sul, RS, Brazil.
出版信息
Braz J Otorhinolaryngol. 2020 Nov-Dec;86(6):763-766. doi: 10.1016/j.bjorl.2019.06.002. Epub 2019 Jul 2.
INTRODUCTION
Total rhinectomy is an uncommon procedure for the treatment of nasal malignancies, usually reserved for locally advanced tumors. There are few case series studying total rhinectomy in the literature, reporting conflicting results about recurrence and metastasis.
OBJECTIVE
Evaluate prognosis of total rhinectomy cases for malignant neoplasia in our institution.
METHODS
Retrospective review from January 2013 to September 2018, including all patients undergoing total rhinectomy in our Institution, under the care of the Head and Neck surgical team.
RESULTS
Ten patients were included, two men and eight women. The mean patient age was 71.6 years old. The majority had nasal skin (8 cases) carcinomas. Squamous cell carcinoma was present in seven cases. In total, six cases had regional metastasis, in a median period of 14.3 months. The overall mortality and disease specific mortality was 50% and 30%, respectively, in a median follow-up of 45.7 months.
CONCLUSION
We observed high overall and disease-specific mortality among cases with advanced nasal malignancies undergoing total rhinectomy.
引言
全鼻切除术是治疗鼻腔恶性肿瘤的一种不常见的方法，通常保留用于局部晚期肿瘤。文献中有少数关于全鼻切除术的病例系列研究，报告了关于复发和转移的相互矛盾的结果。
目的
评估我们机构中全鼻切除术治疗恶性肿瘤的病例的预后。
方法
回顾性分析 2013 年 1 月至 2018 年 9 月期间在我们机构接受全鼻切除术的所有患者，这些患者由头颈部外科团队负责治疗。
结果
共纳入 10 例患者，其中 2 例为男性，8 例为女性。患者的平均年龄为 71.6 岁。大多数为鼻皮肤（8 例）癌。7 例为鳞状细胞癌。总共有 6 例发生区域性转移，中位时间为 14.3 个月。中位随访 45.7 个月时，总死亡率和疾病特异性死亡率分别为 50%和 30%。
结论
我们观察到接受全鼻切除术治疗晚期鼻腔恶性肿瘤的患者总体死亡率和疾病特异性死亡率较高。
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