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肋骨骨折患者死亡率的预测因素

Predictors of mortality in patients with rib fractures.

作者信息

Marini Corrado Paolo, Petrone Patrizio, Soto-Sánchez Ana, García-Santos Esther, Stoller Christy, Verde Juan

机构信息

Department of Surgery, New York Medical College, Valhalla, NY, USA.

Department of Surgery - NYU Winthrop Hospital, NYU Long Island School of Medicine, 222 Station Plaza North, Suite 300, Mineola, Long Island, NY, 11501, USA.

出版信息

Eur J Trauma Emerg Surg. 2021 Oct;47(5):1527-1534. doi: 10.1007/s00068-019-01183-5. Epub 2019 Jul 19.

Abstract

BACKGROUND

The aim of this study was to identify risk factors for morbidity and mortality in patients with rib fractures with focus on identifying a more exact age-dependent cut-off for increased morbidity and mortality.

METHODS

Retrospective study of patients 16 years or older with rib fractures from blunt trauma.

EXCLUSION CRITERIA

patients undergoing rib plating. Initial chest X-ray and Computed Tomography (CT) scans were re-read for the number of rib fractures (NRF) and presence of pulmonary contusion (PC). Data included demographics, mechanism of injury (MOI), NRF, associated injuries, Injury Severity Score (ISS), Glasgow Coma Scale (GCS), Geriatric Trauma Outcome Score (GTOS), presence of pneumothorax, hemothorax, hemo-pneumothorax, PC, Adult Respiratory Distress Syndrome (ARDS), pulmonary complications (ventilator-associated pneumonia, nosocomial pneumonia), and mortality. PC was quantified from CT scans with Mimics. Continuous data were analyzed using Student's t test. Variables significantly different by univariate analysis were analyzed by logistic regression analysis.

RESULTS

The study group consisted of 1188 adult trauma patients admitted during a 2-year period; 800 males and 388 females, with a mean age of 54 ± 21. MOI: MVC, 735 (61.8%); falls, 364 (30.6%); other: 89. Mean NRF, 4 ± 2; GCS, GTOS, and ISS, 15 (15-15), 101 (82-124), and 19 ± 9, respectively. Incidence of PC was 329 (27.7%); PTX, HTX, and HTX/PTX, 264 (20.2%), 57 (4.8%), and 147 (12.4%). Flail chest, in 17 (1.4%); 321 required mechanical ventilation. Age, GCS, male gender, and ISS but not NRF and/or PC were predictive of mortality.

CONCLUSIONS

Increased mortality in patients with rib fractures starts at 65 years of age without a further increase until age ≥ 80. NRF does not predict increased mortality independent of age. Severe TBI is the most common cause of death in patients 16-75 years, as opposed to respiratory complications in patients 80 years-old or greater.

摘要

背景

本研究旨在确定肋骨骨折患者发病和死亡的危险因素,重点是确定更准确的与年龄相关的发病和死亡风险增加的临界值。

方法

对16岁及以上因钝性创伤导致肋骨骨折的患者进行回顾性研究。

排除标准

接受肋骨钢板固定术的患者。重新读取初始胸部X线和计算机断层扫描(CT),以确定肋骨骨折数量(NRF)和肺挫伤(PC)的存在情况。数据包括人口统计学资料、损伤机制(MOI)、NRF、相关损伤、损伤严重程度评分(ISS)、格拉斯哥昏迷量表(GCS)、老年创伤结局评分(GTOS)、气胸、血胸、血气胸、PC、成人呼吸窘迫综合征(ARDS)、肺部并发症(呼吸机相关性肺炎、医院获得性肺炎)及死亡率。通过Mimics软件从CT扫描中对PC进行量化。连续数据采用学生t检验进行分析。单因素分析中有显著差异的变量通过逻辑回归分析进行分析。

结果

研究组由2年内收治的1188例成年创伤患者组成;男性800例,女性388例,平均年龄54±21岁。损伤机制:机动车碰撞伤735例(61.8%);跌倒364例(30.6%);其他89例。平均NRF为4±2;GCS、GTOS和ISS分别为15(15 - 15)、101(82 - 124)和19±9。PC发生率为329例(27.7%);气胸、血胸和血气胸分别为264例(20.2%)、57例(4.8%)和147例(12.4%)。连枷胸17例(1.4%);321例需要机械通气。年龄、GCS、男性性别和ISS可预测死亡率,而NRF和/或PC不能。

结论

肋骨骨折患者死亡率增加始于65岁,直至80岁及以上才进一步上升。NRF不能独立于年龄预测死亡率增加。严重创伤性脑损伤是16 - 75岁患者最常见的死亡原因,而80岁及以上患者的死亡原因则是呼吸并发症。

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