Mohseni Shahin, Forssten Maximilian Peter, Mohammad Ismail Ahmad, Cao Yang, Hildebrand Frank, Sarani Babak, Ribeiro Marcelo Af
Orebro universitet Fakulteten for medicin och halsa, Orebro, Sweden.
Department of Surgery, Sheikh Shakhbout Medical City-Mayo Clinic, Abu Dhabi, UAE.
Trauma Surg Acute Care Open. 2024 Feb 7;9(1):e001206. doi: 10.1136/tsaco-2023-001206. eCollection 2024.
Studies have shown an increased risk of morbidity in elderly patients suffering rib fractures from blunt trauma. The association between frailty and rib fractures on adverse outcomes is still ill-defined. In the current investigation, we sought to delineate the association between frailty, measured using the Orthopedic Frailty Score (OFS), and outcomes in geriatric patients with isolated rib fractures.
All geriatric (aged 65 years or older) patients registered in the 2013-2019 Trauma Quality Improvement database with a conservatively managed isolated rib fracture were considered for inclusion. An isolated rib fracture was defined as the presence of ≥1 rib fracture, a thorax Abbreviated Injury Scale (AIS) between 1 and 5, an AIS ≤1 in all other regions, as well as the absence of pneumothorax, hemothorax, or pulmonary contusion. Based on patients' OFS, patients were classified as non-frail (OFS 0), pre-frail (OFS 1), or frail (OFS ≥2). The prevalence ratio (PR) of composite complications, in-hospital mortality, failure-to-rescue (FTR), and intensive care unit (ICU) admission between the OFS groups was determined using Poisson regression models to adjust for potential confounding.
A total of 65 375 patients met the study's inclusion criteria of whom 60% were non-frail, 29% were pre-frail, and 11% were frail. There was a stepwise increased risk of complications, in-hospital mortality, and FTR from non-frail to pre-frail and frail. Compared with non-frail patients, frail patients exhibited a 87% increased risk of in-hospital mortality [adjusted PR (95% CI): 1.87 (1.52-2.31), p<0.001], a 44% increased risk of complications [adjusted PR (95% CI): 1.44 (1.23-1.67), p<0.001], a doubling in the risk of FTR [adjusted PR (95% CI): 2.08 (1.45-2.98), p<0.001], and a 17% increased risk of ICU admission [adjusted PR (95% CI): 1.17 (1.11-1.23), p<0.001].
There is a strong association between frailty, measured using the OFS, and adverse outcomes in geriatric patients managed conservatively for rib fractures.
研究表明,因钝性创伤导致肋骨骨折的老年患者发病风险增加。虚弱与肋骨骨折对不良结局的关联仍不明确。在本研究中,我们试图阐明使用骨科虚弱评分(OFS)衡量的虚弱与老年孤立性肋骨骨折患者结局之间的关联。
纳入2013 - 2019年创伤质量改进数据库中登记的所有保守治疗孤立性肋骨骨折的老年(65岁及以上)患者。孤立性肋骨骨折定义为存在≥1处肋骨骨折、胸部简明损伤量表(AIS)评分为1至5分、所有其他部位AIS≤1分,且无气胸、血胸或肺挫伤。根据患者的OFS,将患者分为非虚弱(OFS 0)、虚弱前期(OFS 1)或虚弱(OFS≥2)。使用泊松回归模型确定OFS组之间复合并发症、院内死亡率、抢救失败(FTR)和重症监护病房(ICU)入院的患病率比(PR),以调整潜在的混杂因素。
共有65375例患者符合研究纳入标准,其中60%为非虚弱患者,29%为虚弱前期患者,11%为虚弱患者。从非虚弱到虚弱前期再到虚弱,并发症、院内死亡率和FTR的风险呈逐步增加。与非虚弱患者相比,虚弱患者院内死亡率风险增加87%[调整后PR(95%CI):1.87(1.52 - 2.31),p<0.001],并发症风险增加44%[调整后PR(95%CI):1.44(1.23 - 1.67),p<0.001],FTR风险翻倍[调整后PR(95%CI):2.08(1.45 - 2.98),p<0.001],ICU入院风险增加17%[调整后PR(95%CI):1.17(1.11 - 1.23),p<0.001]。
使用OFS衡量的虚弱与老年肋骨骨折保守治疗患者的不良结局之间存在密切关联。