Arora Tavish, Mantur P G, Bidri R C, Mulimani M S
Post Graduate, Department of Medicine, Shri B.M. Patil Medical College Hospital & Research Centre, Karnataka, Corresponding Author.
Associate Professor, Department of Medicine, Shri B.M. Patil Medical College Hospital & Research Centre, Karnataka.
J Assoc Physicians India. 2018 Jul;66(7):66-68.
Stroke is a growing disease and it is the second common cause of death in the world after coronary heart disease especially in the elderly. In patients with acute stroke hyperuricemia was significantly higher than normal population with associated dyslipidemia. Hyperuricemia has been associated with decreased amount of HDL cholesterol and increased amounts of triglycerides and LDL cholesterol.
:Serum uric acid levels and serum lipid levels in patients with ischemic cerebrovascular accident.
This was a cross-sectional study carried out between January 2015 - June 2016, which included 60 cases of acute ischemic stroke. Serum uric acid levels and serum lipid levels was done in all the patients and was statistically analyzed.
A total of 60 patients with ischemic stroke were included in the study. Out of which 43 (71.7%) were males and 17 (28.3%) were females. The mean age of the patients was 63.2 ±14.8. Mean serum uric acid levels in the patients studied was 5.5 ± 1.7, and 18 patients (30%) were hyperuricemic. Serum uric acid levels were significantly higher in females (6.2 ± 1.9) compared to the males (5.2 ±1.6). It was predominant in the age group between 56-70 years. Dyslipidemia was seen in 49 (81.7%) patients (Males were 36 and females were 13).. More than one lipid parameter was seen to be deranged in 10 male patients and 4 female patients. Of them 87.75% of patients had low HDL levels, 36.73%, 10.20% and 8.16% patient had high cholesterol, triglycerides and LDL levels respectively. The study also showed that 15 patients had both hyperuricemia and dyslipidemia.
Hyperuricemia and its accompanying dyslipidemia can be considered as the risk factor for acute ischemic stroke.
中风是一种日益常见的疾病，是继冠心病之后世界上第二大常见死因，在老年人中尤为如此。急性中风患者的高尿酸血症明显高于正常人群，并伴有血脂异常。高尿酸血症与高密度脂蛋白胆固醇含量降低以及甘油三酯和低密度脂蛋白胆固醇含量增加有关。
缺血性脑血管意外患者的血清尿酸水平和血脂水平。
这是一项于2015年1月至2016年6月进行的横断面研究，纳入了60例急性缺血性中风患者。对所有患者进行血清尿酸水平和血脂水平检测，并进行统计学分析。
本研究共纳入60例缺血性中风患者。其中男性43例（71.7%），女性17例（28.3%）。患者的平均年龄为63.2±14.8岁。所研究患者的平均血清尿酸水平为5.5±1.7，18例患者（30%）为高尿酸血症。女性患者的血清尿酸水平（6.2±1.9）明显高于男性患者（5.2±1.6）。在56 - 70岁年龄组中最为常见。49例（81.7%）患者出现血脂异常（男性36例，女性13例）。10例男性患者和4例女性患者的不止一项血脂参数出现紊乱。其中87.75%的患者高密度脂蛋白水平较低，36.73%、10.20%和8.16% 的患者分别出现高胆固醇、高甘油三酯和低密度脂蛋白水平。研究还表明，15例患者同时患有高尿酸血症和血脂异常。
高尿酸血症及其伴随的血脂异常可被视为急性缺血性中风的危险因素。
