Iseev L R, Mednykh A Ia, Vorob'ev V E, Abdrakhmanov V R
Kosm Biol Aviakosm Med. 1988 Mar-Apr;22(2):16-20.
Using the rebreathing method, CO2 sensitivity of the respiration regulation system was investigated during a year-long enclosure study and head-down tilt tests of varying duration (up to 120 days). During the exposures CO2 and H+ were built up in the body. In the course of the enclosure study CO2 sensitivity was reduced. During bed rest experiments this parameter changed differently: it increased on day 7 and significantly decreased on days 55 to 100. These findings show that respiration regulation may vary markedly and indicate that it is worthwhile to carry out similar investigations in an actual space flight.
采用重复呼吸法，在为期一年的密闭研究和不同时长（最长120天）的头低位倾斜试验中，对呼吸调节系统的二氧化碳敏感性进行了研究。在暴露过程中，体内二氧化碳和氢离子蓄积。在密闭研究过程中，二氧化碳敏感性降低。在卧床休息实验中，该参数变化不同：在第7天增加，在第55至100天显著降低。这些发现表明，呼吸调节可能会有显著变化，并表明在实际太空飞行中进行类似研究是值得的。
