Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY, 14203, United States.
College of Liberal Arts & Sciences, Wayne State University, 4841 Cass Avenue, Detroit, MI, 48201, United States.
Drug Alcohol Depend. 2019 Sep 1;202:93-103. doi: 10.1016/j.drugalcdep.2019.07.001. Epub 2019 Jul 8.
The prevalence of cigarette smoking among individuals with a history of substance use disorders (SUDs) remains up to four times higher than those without a history of SUDs. More than half of individuals who attain sustained remission from SUDs will die of tobacco-related diseases. The aim of this secondary data analysis was to compare the risk for smoking relapse among smokers with no history of SUDs and smokers in recovery from SUDs after multi-component, cognitive-behavioral treatment for tobacco dependence.
Participants were randomized to receive 6 sessions of multicomponent cognitive-behavioral therapy (adapted for lower socioeconomic groups or standard), 8 weeks of nicotine patches, and were followed for 6 months in the parent randomized clinical trial. Participants passed a urine drug test prior to enrollment. Recovery was assessed at baseline by self-report to the question, "Do consider yourself in recovery from drugs or alcohol?" Relapse was defined as any smoking for 7 consecutive days.
Participants were primarily lower SES and identified as racial and/or ethnic minorities. Cox proportional hazards models revealed that the risk of smoking relapse following tobacco dependence treatment was greater among smokers in long-term (HR: 1.44; 95% CI: 1.01, 2.05) and short-term (HR: 1.98; 95% CI: 1.30, 3.03) recovery than for smokers with no history of SUDs.
Our findings indicate that smokers in recovery from SUDs have 1.5-2 times the risk of relapse than smokers with no history of SUDs. More effective relapse prevention interventions are needed for this vulnerable, high-risk group of smokers.
有物质使用障碍(SUD)病史的个体的吸烟率仍然比没有 SUD 病史的个体高 4 倍。超过一半的 SUD 患者在获得持续缓解后将死于与烟草相关的疾病。本二次数据分析的目的是比较无 SUD 病史的吸烟者和 SUD 康复者在接受多成分认知行为治疗戒烟后复吸的风险。
参与者被随机分配接受 6 次多成分认知行为治疗(适应于较低社会经济群体或标准)、8 周尼古丁贴片治疗,并在父母随机临床试验中随访 6 个月。参与者在入组前通过尿液药物检测。恢复情况通过自我报告的问题进行评估:“您是否认为自己正在从药物或酒精中康复?”复发定义为连续 7 天吸烟。
参与者主要来自低社会经济群体,并且被确定为种族和/或少数民族。Cox 比例风险模型显示,在长期(HR:1.44;95%CI:1.01,2.05)和短期(HR:1.98;95%CI:1.30,3.03)康复后,吸烟者的吸烟复发风险高于无 SUD 病史的吸烟者。
我们的发现表明,SUD 康复后的吸烟者复发的风险比没有 SUD 病史的吸烟者高 1.5-2 倍。需要为这个脆弱、高风险的吸烟者群体提供更有效的复发预防干预措施。