Department of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Neuroscience, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Department of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Neuroscience, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
J Surg Res. 2019 Dec;244:444-455. doi: 10.1016/j.jss.2019.06.052. Epub 2019 Jul 18.
Current perioperative patient care aims to maintain homeostasis by attenuation of the stress response to surgery, as a more vigorous stress response can have detrimental effects on postoperative recovery. This systematic review and meta-analysis aims to assess the effect of perioperative music on the physiological stress response to surgery.
The Embase, Medline Ovid, Cochrane Central, Web of Science, and Google Scholar databases were searched from inception date until February 5, 2019, using a systematic literature search following the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines for randomized controlled trials investigating the effect of music before, during, and/or after surgery in adult surgical patients on the stress response to surgery. Meta-analysis was performed using a random effects model and pooled standardized mean differences were calculated with 95% confidence intervals. This study was registered in the PROSPERO database (CRD42018097060).
The literature search identified 1076 articles. Eighteen studies (1301 patients) were included in the systematic review, of which eight were included in the meta-analysis. Perioperative music attenuated the neuroendocrine cortisol stress response to surgery (pooled standardized mean difference -0.30, [95% confidence interval -0.53 to -0.07], P = 0.01, I = 0).
Perioperative music can attenuate the neuroendocrine stress response to surgery.
目前的围手术期患者护理旨在通过减轻手术应激反应来维持内环境稳定，因为更强烈的应激反应可能对术后恢复产生不利影响。本系统评价和荟萃分析旨在评估围手术期音乐对手术应激反应的生理影响。
从建库日期到 2019 年 2 月 5 日，我们使用系统文献检索，根据系统评价和荟萃分析的首选报告项目，检索了 Embase、Medline Ovid、Cochrane 中心、Web of Science 和 Google Scholar 数据库，以调查术前、术中和/或术后音乐对成人手术患者手术应激反应的影响的随机对照试验。使用随机效应模型进行荟萃分析，并计算合并标准化均数差值及其 95%置信区间。本研究在 PROSPERO 数据库（CRD42018097060）中进行了注册。
文献检索共确定了 1076 篇文章。18 项研究（1301 名患者）纳入了系统评价，其中 8 项研究纳入了荟萃分析。围手术期音乐可减轻手术的神经内分泌皮质醇应激反应（合并标准化均数差值 -0.30，[95%置信区间 -0.53 至 -0.07]，P = 0.01，I² = 0）。
围手术期音乐可以减轻手术的神经内分泌应激反应。
