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内镜评分系统用于评估和监测克罗恩病的疾病活动度。

Endoscopic scoring systems for the evaluation and monitoring of disease activity in Crohn's disease.

机构信息

Division of Pediatric Gastroenterology, Department of Pediatrics, McMaster University Medical Center (MUMC), McMaster Children's Hospital, 1200 Main St. W, 3A, Hamilton, ON, Canada; Division of Gastroenterology, Department of Medicine, McGill University Health Center (MUHC), Montreal General Hospital, 1650 Cedar Ave, C7-200, Montreal, QC, H3G 1A4, Canada.

Division of Gastroenterology, Department of Medicine, McGill University Health Center (MUHC), Montreal General Hospital, 1650 Cedar Ave, C7-200, Montreal, QC, H3G 1A4, Canada.

出版信息

Best Pract Res Clin Gastroenterol. 2019 Feb-Apr;38-39:101616. doi: 10.1016/j.bpg.2019.05.003. Epub 2019 May 28.

Abstract

Crohn's disease is a chronic relapsing idiopathic condition that can affect any part of the gastrointestinal tract. It has been shown that mucosal healing is associated with improved clinical outcomes such as reduced risk of surgery, hospitalization and complications. Nowadays mucosal healing is considered the optimal target of medical therapy. To evaluate the mucosa in an objective and standardized manner, it is important to rely on accurate and validated endoscopic scores. The Crohn's disease endoscopic index of severity, the simple endoscopic score for Crohn's disease as well as the Rutgeerts score will be reviewed. Their clinical implications and limitations will be discussed.

摘要

克罗恩病是一种慢性复发性特发性疾病,可影响胃肠道的任何部位。研究表明,黏膜愈合与改善临床结局相关,如降低手术、住院和并发症的风险。目前,黏膜愈合被认为是医学治疗的最佳目标。为了客观和标准化地评估黏膜,依赖准确和经过验证的内镜评分非常重要。本文将回顾克罗恩病内镜严重程度指数、克罗恩病简单内镜评分和 Rutgeerts 评分,并讨论其临床意义和局限性。

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