Hinshaw D B, Fahmy J L, Peckham N, Thompson J R, Hasso A N, Holshouser B, Paprocki T
Section of Magnetic Resonance Sciences, Loma Linda University, CA 92354.
AJNR Am J Neuroradiol. 1988 May-Jun;9(3):483-6.
Fourteen patients studied with MR imaging were found, incidentally, to have unusually bright, large choroid plexus glomera on T2-weighted sequences. A group of 167 patients was then examined retrospectively for size and intensity of the choroid plexus glomera on T2-weighted images. In the latter group of 167 patients, 66 (39.5%) had bright choroid plexus glomera. Of those who had bright choroid plexus glomera, eight of the 14 initial group and 11 of the 66 patients studied retrospectively had previous CT scans. The typical CT appearance of these bright glomera consisted of nonenhancing central regions of low (but not negative) attenuation with peripheral calcifications in the majority. The remainder showed noncalcified glomera. Fifty-two glomera were obtained at autopsy and examined retrospectively. Eight showed small, variably sized masses with lipid deposits, neuroepithelial microcysts, and peripheral psammoma body calcifications. One patient who died had a bright choroid plexus glomus on MR, and his glomera showed the same pathologic findings. The autopsy findings were believed to be typical pathologically for early xanthogranulomata formation. These early xanthogranulomatous changes appear to be of little clinical significance but must be differentiated from other lesions that can produce bright or enlarged choroid plexus glomera on MR.
在接受磁共振成像(MR)检查的14名患者中,偶然发现其在T2加权序列上有异常明亮且较大的脉络丛球。随后对167名患者进行回顾性检查,观察其T2加权图像上脉络丛球的大小和信号强度。在这167名患者中,66名(39.5%)有明亮的脉络丛球。在那些有明亮脉络丛球的患者中,最初14名患者中有8名以及回顾性研究的66名患者中有11名曾接受过CT扫描。这些明亮球的典型CT表现为大多数中央区域无强化,呈低(但非负)密度,周边有钙化。其余的显示为非钙化球。尸检获得了52个球并进行回顾性检查。8个显示为大小不一的小肿块,有脂质沉积、神经上皮微囊肿和周边砂粒体钙化。一名死亡患者的MR图像上有一个明亮的脉络丛球,其球显示出相同的病理表现。尸检结果在病理上被认为是早期黄色肉芽肿形成的典型表现。这些早期黄色肉芽肿性改变似乎临床意义不大,但必须与其他在MR上可产生明亮或增大的脉络丛球的病变相鉴别。