Barkovich A J, Kjos B O
Department of Radiology, Letterman Army Medical Center, Presidio of San Francisco, CA 94129-6700.
AJNR Am J Neuroradiol. 1988 May-Jun;9(3):487-91.
Sixty-three patients, 3 days to 12 months old, were examined by MR imaging to evaluate the normal development of the corpus callosum in the first year of life. During the first month of life the corpus callosum is uniformly thin and of the same signal intensity as white matter throughout the brain. During the second month, a variable spurt of growth occurs in the genu, followed by a similar period of rapid growth in the splenium between 4-6 months of age. High signal intensity on T1-weighted images related to the myelination process begins to appear in the splenium by about 4 months and in the genu by about 6 months. The corpus callosum has an adult appearance on sagittal scans by about 8 months of age.
对63例年龄在3天至12个月的患儿进行了磁共振成像（MR）检查，以评估生命第一年胼胝体的正常发育情况。在出生后的第一个月，胼胝体整体较薄，其信号强度与全脑白质相同。在第二个月，胼胝体膝部出现不同程度的快速生长，随后在4至6个月大时，压部也经历类似的快速生长阶段。与髓鞘形成过程相关的T1加权图像上的高信号强度大约在4个月时开始出现在压部，6个月左右出现在膝部。在矢状位扫描上，胼胝体在大约8个月大时呈现出成人的形态。
