Calodioscurins A 和 B，两种新型异戊烯基黄烷酮，来自 P.F. Stevens 的茎皮。
Calodioscurins A and B, two new isoprenylated xanthones from the stem bark of P.F. Stevens.
机构信息
Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia.
出版信息
Nat Prod Res. 2021 Apr;35(7):1153-1158. doi: 10.1080/14786419.2019.1643864. Epub 2019 Jul 22.
Two new isoprenylated xanthones, calodioscurin A () and B () were isolated from the stem bark of P.F. Stevens along with two known isoprenylated 4-phenylcoumarins, apetalolide () and methyl inophyllum P (). The structures of two new compounds were determined based on their HRESIMS, IR, UV, 1D and 2D NMR spectral data. Compounds - were assayed on P-388 cells, compound showed IC value 11.5 μM and categorised moderate activity.
从 P.F. Stevens 的茎皮中分离得到两种新的异戊烯基黄酮，即 calodioscurin A () 和 B ()，以及两种已知的异戊烯基 4-苯基香豆素，apetalolide () 和 methyl inophyllum P ()。根据它们的 HRESIMS、IR、UV、1D 和 2D NMR 光谱数据确定了两种新化合物的结构。对化合物 - 进行了 P-388 细胞测定，化合物 显示 IC 值为 11.5 μM，归类为中度活性。
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