Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia.
Nat Prod Res. 2021 Apr;35(7):1153-1158. doi: 10.1080/14786419.2019.1643864. Epub 2019 Jul 22.
Two new isoprenylated xanthones, calodioscurin A () and B () were isolated from the stem bark of P.F. Stevens along with two known isoprenylated 4-phenylcoumarins, apetalolide () and methyl inophyllum P (). The structures of two new compounds were determined based on their HRESIMS, IR, UV, 1D and 2D NMR spectral data. Compounds - were assayed on P-388 cells, compound showed IC value 11.5 μM and categorised moderate activity.
从 P.F. Stevens 的茎皮中分离得到两种新的异戊烯基黄酮，即 calodioscurin A () 和 B ()，以及两种已知的异戊烯基 4-苯基香豆素，apetalolide () 和 methyl inophyllum P ()。根据它们的 HRESIMS、IR、UV、1D 和 2D NMR 光谱数据确定了两种新化合物的结构。对化合物 - 进行了 P-388 细胞测定，化合物 显示 IC 值为 11.5 μM，归类为中度活性。
