Silva Glauber T, Tian Liangfei, Franklin Amanda, Wang Xuejing, Han Xiaojun, Mann Stephen, Drinkwater Bruce W
Physical Acoustics Group, Instituto de Física, Universidade Federal de Alagoas, Maceió, AL 57072-970, Brazil.
Centre for Protolife Research and Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, United Kingdom.
Phys Rev E. 2019 Jun;99(6-1):063002. doi: 10.1103/PhysRevE.99.063002.
We use an ultrasonic standing wave to simultaneously trap and deform thousands of soft lipid vesicles immersed in a liquid solution. In our device, acoustic radiation stresses comparable in magnitude to those generated in optical stretching devices are achieved over a spatial extent of more than ten acoustic wavelengths. We solve the acoustic scattering problem in the long-wavelength limit to obtain the radiation stress. The result is then combined with thin-shell elasticity theory to form expressions that relate the deformed geometry to the applied acoustic field intensity. Using observation of the deformed geometry and this model, we rapidly extract mechanical properties, such as the membrane Young's modulus, from populations of lipid vesicles.
我们使用超声波驻波同时捕获并使浸没在液体溶液中的数千个软脂质囊泡变形。在我们的装置中，在超过十个声波波长的空间范围内，实现了与光学拉伸装置中产生的辐射应力大小相当的声辐射应力。我们求解长波长极限下的声散射问题以获得辐射应力。然后将结果与薄壳弹性理论相结合，形成将变形几何形状与所施加的声场强度相关联的表达式。通过观察变形几何形状并利用该模型，我们从脂质囊泡群体中快速提取出诸如膜杨氏模量等力学性能。
