Tsuruo Y, Hökfelt T, Visser T J
Department of Histology, Karolinska Institute, Stockholm, Sweden.
Brain Res. 1988 Apr 26;447(1):183-7. doi: 10.1016/0006-8993(88)90983-3.
Thyrotropin-releasing hormone (TRH)-like immunoreactivity was examined in the rat olfactory bulb by an immunohistochemical method using antiserum against the tripeptide TRH. TRH-immunoreactive neurons and neuronal processes were localized in both main and accessory olfactory bulb, including the glomerular layer, external plexiform layer, mitral cell body layer, internal plexiform layer and granule cell layer. However, no TRH-positive structures were observed in the olfactory nerve layer. The present study demonstrates that TRH is located in several neuronal populations in the olfactory bulb, and that this peptide thus may be involved in the processing of information in the olfactory system.
采用抗三肽促甲状腺激素释放激素（TRH）的抗血清，通过免疫组织化学方法检测大鼠嗅球中TRH样免疫反应性。TRH免疫反应性神经元和神经突位于主嗅球和副嗅球中，包括肾小球层、外丛状层、二尖瓣细胞体层、内丛状层和颗粒细胞层。然而，在嗅神经层未观察到TRH阳性结构。本研究表明，TRH存在于嗅球中的多个神经元群体中，因此该肽可能参与嗅觉系统中的信息处理。
