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胰岛素治疗飞行员飞行期间血糖水平的连续血糖监测

Continuous Glucose Monitoring for In-Flight Measurement of Glucose Levels of Insulin-Treated Pilots.

作者信息

Strollo Felice, Simons Ries, Mambro Andrea, Strollo Giovanna, Gentile Sandro

出版信息

Aerosp Med Hum Perform. 2019 Aug 1;90(8):735-737. doi: 10.3357/AMHP.5315.2019.

Abstract

Due to the risk of hypoglycemia-related incapacitation, diabetic pilots requiring insulin are assessed as unfit according to the International Civil Aviation Organization and most national authorities. Some authorities, such as those from Canada, the United Kingdom, and the United States, permit selected insulin-treated pilots (ITDM-pilots) to fly subject to a protocol requiring pre- and in-flight capillary glucose measurements to show safe levels (>100-<300 mg · dl). Critics of such permission question the practicability of these in-flight measurements and whether clinically desired glycemic targets can be achieved while keeping glucose levels in the safe range. Subcutaneous continuous glucose monitoring (CGM) has recently been approved by the FDA as a stand-alone method to provide accurate glucose levels and treatment decision guidance in patients. This commentary considers that use of CGM by ITDM pilots facilitates practicability and recording of in-flight glucose measurements and facilitates achievement of clinically desired glycemic targets without increasing hypoglycemia risks.

摘要

由于存在与低血糖相关的失能风险,根据国际民用航空组织和大多数国家当局的规定,需要注射胰岛素的糖尿病飞行员被判定为不适宜飞行。一些当局,如加拿大、英国和美国的当局,允许经过挑选的接受胰岛素治疗的飞行员(ITDM飞行员)飞行,但需遵循一项方案,该方案要求在飞行前和飞行中进行毛细血管血糖测量,以显示血糖水平处于安全范围(>100 - <300 mg·dl)。对此类许可持批评态度的人质疑这些飞行中测量的实用性,以及在将血糖水平保持在安全范围内的同时是否能够实现临床上期望的血糖目标。皮下连续血糖监测(CGM)最近已被美国食品药品监督管理局(FDA)批准为一种独立方法,可为患者提供准确的血糖水平和治疗决策指导。本评论认为,ITDM飞行员使用CGM有助于提高飞行中血糖测量的实用性和记录,并有助于在不增加低血糖风险的情况下实现临床上期望的血糖目标。

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