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持续葡萄糖监测(CGM)作为胰岛素治疗糖尿病商业航空飞行员及利益相关者/监管机构的工具的技术创新:改进指令的新契机?

Technological innovation of Continuous Glucose Monitoring (CGM) as a tool for commercial aviation pilots with insulin-treated diabetes and stakeholders/regulators: A new chance to improve the directives?

作者信息

Strollo F, Furia A, Verde P, Bellia A, Grussu M, Mambro A, Petrelli M D, Gentile S

机构信息

AMD (Associazione Medici Diabetologi), ESAM (European Society of Aerospace Medicine) and IRCCS San Raffaele Pisana, Rome, Italy.

ENAC (Italian National Civil Aviation Authority), Aeromedical Section, Rome, Italy.

出版信息

Diabetes Res Clin Pract. 2021 Feb;172:108638. doi: 10.1016/j.diabres.2020.108638. Epub 2020 Dec 22.

Abstract

Civil aviation pilots who develop insulin-treated diabetes and want to renew a Commercial Pilot License (CPL) represent a medical, social and regulatory problem. This depends on justified concerns about hypoglycemia, the most threatening event for people who carry out jobs requiring a high level of concentration and reliability. This negatively affects social and working aspects of pilots' lives, who have a high profile and a high-cost professional qualification. It could be possible now to revise this attitude thanks to the availability of Continuous Glucose Monitoring (CGM) devices. CGM clearly showed to prevent hypoglycemic events in insulin-treated diabetic patients by allowing strict monitoring and trend prediction of glucose levels. By systematizing available data on such devices and present regulations in CPL issuance worldwide, our review can be used as handy tool for a fruitful discussion among the scientific community, national and international civil aviation regulators, stakeholders and pilots, aimed at evaluating the evidence-based opportunity to revise CPL issuance criteria for insulin-treated diabetic pilots. For the above-mentioned reasons, there are, among the regulatory administrations of Civil Aviation around the globe, several different approaches and limitations set for the subjects with insulin-treated diabetes who want to obtain, or renew, a CPL.

摘要

患有需胰岛素治疗的糖尿病且希望续签商业飞行员执照(CPL)的民航飞行员,构成了一个医学、社会和监管方面的问题。这源于对低血糖的合理担忧,低血糖对从事需要高度专注和可靠性工作的人来说是最具威胁性的事件。这对飞行员的社会和工作生活产生了负面影响,他们有着较高的知名度和高成本的专业资质。由于连续血糖监测(CGM)设备的出现,现在有可能改变这种态度。CGM通过允许严格监测血糖水平和预测血糖趋势,清楚地显示出可预防胰岛素治疗的糖尿病患者发生低血糖事件。通过整理关于此类设备的现有数据以及全球CPL颁发的现行规定,我们的综述可作为一个便捷工具,用于科学界、国家和国际民航监管机构、利益相关者及飞行员之间富有成效的讨论,旨在评估基于证据修改胰岛素治疗的糖尿病飞行员CPL颁发标准的机会。出于上述原因,在全球民航监管部门中,对于患有需胰岛素治疗的糖尿病且希望获得或续签CPL的人员,存在几种不同的方法和限制。

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