Department of Pediatrics, Division of Neonatology and Developmental Biology, Neonatal Research Center of the UCLA Children's Discovery and Innovation Institute, David Geffen School of Medicine UCLA, Los Angeles, CA, United States.
Harvard Medical School, Boston, MA, United States; Department of Surgery and the Vascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Semin Perinatol. 2019 Nov;43(7):151155. doi: 10.1053/j.semperi.2019.06.003. Epub 2019 Jun 22.
Parenteral nutrition and intravenous lipid emulsions are essential for promoting optimal nutrition in the neonatal intensive care unit. However, long-term use of a pure soybean lipid emulsion is associated with a liver disease known as intestinal failure associated liver disease. Over the past several years, the science of lipid emulsions has evolved with a focus on nutritional optimization and disease prevention. This review's purpose is to provide a general overview of the three main components of lipid emulsions, phytosterols, the antioxidant Vitamin E, and polyunsaturated fatty acids, and their contribution to health.
肠外营养和静脉用脂肪乳剂对于促进新生儿重症监护病房中的最佳营养至关重要。然而，长期使用纯大豆脂肪乳剂与一种称为肠衰竭相关肝病的肝病有关。在过去的几年中，脂肪乳剂的科学研究已经发展到关注营养优化和疾病预防。本文综述的目的是提供关于脂肪乳剂的三个主要成分——植物固醇、抗氧化维生素 E 和多不饱和脂肪酸及其对健康的贡献的概述。
