SaBio, Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005 Ciudad Real, Spain.
Faculty of Veterinary Medicine, University of Zaragoza, 50013 Zaragoza, Spain.
Trends Parasitol. 2019 Sep;35(9):725-737. doi: 10.1016/j.pt.2019.06.014. Epub 2019 Jul 19.
Recently, our knowledge of the composition and complexity of tick microbial communities has increased and supports microbial impact on tick biology. Results support a phylogenetic association between ticks and their microbiota across evolution; this is known as phylosymbiosis. Herein, using published datasets, we confirm the existence of phylosymbiosis between Ixodes ticks and their microbial communities. The strong phylosymbiotic signal and the phylogenetic structure of microbial communities associated with Ixodid ticks revealed that phylosymbiosis may be a widespread phenomenon in tick-microbiota evolution. This finding supports the existence of a species-specific tick hologenome with a largely unexplored influence on tick biology and pathogen transmission. These results may provide potential targets for the construction of paratransgenic ticks to control tick infestations and tick-borne diseases.
最近，我们对蜱虫微生物群落的组成和复杂性的了解有所增加，并支持微生物对蜱虫生物学的影响。研究结果支持蜱虫与其微生物群落之间存在跨越进化的系统发育关联；这被称为系统共生。在此，我们使用已发表的数据集证实了硬蜱和它们的微生物群落之间存在系统共生。硬蜱与其微生物群落之间存在强烈的系统共生信号和系统发育结构，表明系统共生可能是蜱虫-微生物群进化中的一种普遍现象。这一发现支持了具有广泛影响的蜱虫全基因组的存在，这对蜱虫生物学和病原体传播有很大的影响，但目前还未被充分探索。这些结果可能为构建转共生蜱虫以控制蜱虫滋生和蜱传疾病提供潜在目标。
