[脾脏对不同脾脏大小小鼠品系肿瘤生长的影响]
[The effect of the spleen on tumor growth in mouse lines with various spleen sizes].
作者信息
von Wallenberg H, Mainusch P, Meyer J, Hammer C
出版信息
Chir Forum Exp Klin Forsch. 1979:169-73.
PMID:313319
Abstract
Selectively raised laboratory mice differ according to spleen size in their immunologic behavior against various tumors. A small spleen and splenectomy reduce tumor growth, whereas a large spleen or additional transfer of tumor antigen-specific spleen cells ("suppressor cells") stimulate tumor incidence.
摘要
选择性培育的实验小鼠在针对各种肿瘤的免疫行为上，根据脾脏大小而有所不同。脾脏小和脾切除会减少肿瘤生长，而脾脏大或额外转移肿瘤抗原特异性脾细胞（“抑制细胞”）则会刺激肿瘤发生率。
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