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静脉葡萄糖耐量试验中葡萄糖 - 胰岛素相互作用延迟模型的分岔分析

Bifurcation analysis in a delay model of IVGTT glucose-insulin interaction.

作者信息

Mohabati Fateme, Molaei MohammadReza

机构信息

Mahani Mathematical Research Center and Department of Pure Mathematics, Shahid Bahonar Kerman University, Kerman, Iran.

出版信息

Theory Biosci. 2020 Feb;139(1):9-20. doi: 10.1007/s12064-019-00298-y. Epub 2019 Jul 22.

Abstract

In this paper, a delayed differential model based on the intravenous glucose tolerance test is considered. The conditions to determine stability or instability of the model's steady state are obtained. We obtain the necessary conditions for the appearance of a bifurcation, and we investigate the direction and stability of the local bifurcation. For this purpose, the normal form theory is used. In addition, the numerical diagrams in the direction of theoretical results are drawn.

摘要

本文考虑了一个基于静脉葡萄糖耐量试验的延迟微分模型。得到了确定该模型稳态稳定性或不稳定性的条件。我们获得了出现分岔的必要条件,并研究了局部分岔的方向和稳定性。为此,使用了范式理论。此外,还绘制了与理论结果方向一致的数值图。

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