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机器人手术与阴道手术治疗盆腔器官脱垂的围手术期结局

Perioperative outcomes after robotic versus vaginal surgery for pelvic organ prolapse.

作者信息

Nguyen John N, Yang Su-Jau T

机构信息

Department of Obstetrics and Gynecology, Southern California Permanente Medical Group, Downey Medical Center, Kaiser Foundation Hospital, 9449 E. Imperial Highway, Suite C327, Downey, CA, 90242, USA.

Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.

出版信息

J Robot Surg. 2020 Jun;14(3):415-421. doi: 10.1007/s11701-019-01006-0. Epub 2019 Jul 22.

Abstract

The objectives of the study were to compare post-anesthesia care unit opioid use and pain scores, surgical and hospitalization times, and perioperative adverse events rates following robotic sacrocolpopexy (RSC) versus transvaginal uterosacral ligament suspension (USLS). This was a retrospective analysis of women 18 years and older who underwent either robotic sacrocolpopexy (n = 87) or transvaginal uterosacral ligament suspension (n = 103) between January 1, 2015 to December 31, 2017 at Downey Medical Center by two surgeons. Data including nurses' verbal pain scores and opioid use were abstracted from electronic medical records. Adverse events were classified using the Clavien-Dindo scale. Women in the robotic group were older (62 ± 8 years vs 58 ± 11 years, p = 0.005), had higher rate of stage III or IV prolapse [49/87 (56%) vs 15/103 (15%), p < 0.0002], lower postoperative pain scores (2.6 ± 1.8 vs 4.2 ± 2.4, p < 0.0001), and used less opioids (26 ± 17 mg morphine dose equivalent vs 35 ± 24 mg morphine dose equivalent, p = 0.005) than those in the transvaginal group. Readmissions and reoperations for adverse events were not significantly different between the RSC and USLS groups [5/87 (6%) vs 12/103 (12%), p = 0.16], respectively. Moreover, Dindo-Clavien scores of II or higher occurred at similar rates between the two groups [20/87 (23%) vs 26/103 (25%), p = 0.72]. However, patients had a higher rate of prolonged urethral catheterization following USLS (0/87) than RSC (6/103) (p = 0.03). Robotic sacrocolpopexy was associated with less immediate postoperative pain and opioid use compared to uterosacral ligament vaginal suspension.

摘要

本研究的目的是比较机器人骶骨阴道固定术(RSC)与经阴道子宫骶骨韧带悬吊术(USLS)后麻醉后护理单元的阿片类药物使用情况和疼痛评分、手术及住院时间,以及围手术期不良事件发生率。这是一项对2015年1月1日至2017年12月31日期间在唐尼医疗中心由两位外科医生进行机器人骶骨阴道固定术(n = 87)或经阴道子宫骶骨韧带悬吊术(n = 103)的18岁及以上女性的回顾性分析。包括护士口头疼痛评分和阿片类药物使用情况的数据从电子病历中提取。不良事件使用Clavien-Dindo量表进行分类。机器人组的女性年龄更大(62±8岁 vs 58±11岁,p = 0.005),III期或IV期脱垂的发生率更高[49/87(56%) vs 15/103(15%),p < 0.0002],术后疼痛评分更低(2.6±1.8 vs 4.2±2.4,p < 0.0001),且使用的阿片类药物更少(吗啡剂量当量为26±17mg vs 35±24mg,p = 0.005),均低于经阴道组。RSC组和USLS组因不良事件再次入院和再次手术的情况无显著差异[5/87(6%) vs 12/103(12%),p = 0.16]。此外,两组中II级或更高的Dindo-Clavien评分发生率相似[20/87(23%) vs 26/103(25%),p = 0.72]。然而,USLS术后尿道导管留置时间延长的发生率(0/87)高于RSC(6/103)(p = 0.03)。与子宫骶骨韧带阴道悬吊术相比,机器人骶骨阴道固定术术后即时疼痛和阿片类药物使用更少。

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