Lúquez Mindiola Adán, Otero Regino William, Schmulson Max
Universidad Nacional de Colombia. Bogotá, Colombia; Centro de Enfermedades Digestivas, GutMédica. Bogotá, Colombia.
Hospital Universitario Nacional de Colombia, Universidad Nacional de Colombia. Bogotá, Colombia; Centro de Gastroenterología y Endoscopia Digestiva, Bogotá - Colombia.
Rev Gastroenterol Peru. 2019 Apr-Jun;39(2):141-152.
Dyspepsia encompasses a set of symptoms that originate in the gastroduodenal region. It is characterized by pain or epigastric burning, early satiety and post-prandial fullness. According to the relationship of symptoms with meals, it is divided into epigastric pain syndrome and postprandial distress syndrome. However, in clinical practice, they frequently overlap. In recent years the paradigm of gastric physiological alterations has been changed and evidence supporting duodenal eosinophilia has increased, as a primary alteration that alters gastric physiology and can induce symptomatology. Every day there is more interest in the alteration of the microbiota. The treatment is based on the suppression of acid, neuromodulators, prokinetics, psychotherapy, alternative and complementary therapies. No treatment is effective in all patients.
消化不良包括一组起源于胃十二指肠区域的症状。其特征为疼痛或上腹部烧灼感、早饱感和餐后饱胀感。根据症状与进餐的关系，可分为上腹痛综合征和餐后不适综合征。然而，在临床实践中，它们常常相互重叠。近年来，胃生理改变的模式已经发生变化，支持十二指肠嗜酸性粒细胞增多的证据也有所增加，这是一种改变胃生理并可诱发症状的主要改变。人们对微生物群的改变越来越感兴趣。治疗方法包括抑制胃酸、使用神经调节剂、促动力药、心理治疗、替代疗法和补充疗法。没有一种治疗方法对所有患者都有效。
