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作为类固醇滥用的一种独特表现:来自一家三级医疗医院的临床真菌学和皮肤镜研究

as a Unique Manifestation of Steroid Abuse: A Clinico-Mycological and Dermoscopic Study from a Tertiary Care Hospital.

作者信息

Singal Archana, Jakhar Deepak, Kaur Ishmeet, Pandhi Deepika, Das Shukla

机构信息

Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital (University of Delhi), Dilshad Garden, Delhi, India.

Department of Microbiology, University College of Medical Sciences and GTB Hospital (University of Delhi), Dilshad Garden, Delhi, India.

出版信息

Indian Dermatol Online J. 2019 Jul-Aug;10(4):422-425. doi: 10.4103/idoj.IDOJ_385_18.

Abstract

BACKGROUND

, characterized by concentric scaly rings simulating is caused by dermatophytes other than . It is reported to occur in patients with steroid abuse and in immunocompromised individuals.

AIM

To study the clinico-mycological profile and dermoscopic features of in immunocompetent patients.

METHODS

We have evaluated 14 consecutive, clinically diagnosed patients of with positive 10% potassium hydroxide (KOH) examination and culture, seen over a period of 6 months. Dermoscopy was performed in all patients. The demographic, clinical, and mycological features of each patient were recorded on a predesigned proforma.

RESULTS

There were seven male and seven female patients with a mean age of 27.6 years and a mean disease duration of 3.8 months. All patients gave a history of application of potent or super-potent topical steroid with or without oral/injectable steroid for varying duration. Culture isolates were complex and in 11 and 3 patients, respectively. Dermoscopic analysis showed features of steroid abuse in majority of the patients.

LIMITATION

A small sample size was the limitation of our study.

CONCLUSION

is a special subset of caused by injudicious and inappropriate use of topical steroid. The typical appearance should alert the dermatologists regarding the possible abuse of steroids. Most common species isolated on culture was complex.

摘要

背景

[疾病名称]由除[某种真菌]以外的皮肤癣菌引起,其特征为同心鳞屑环,类似[某种疾病表现]。据报道,它发生在滥用类固醇的患者和免疫功能低下的个体中。

目的

研究免疫功能正常患者中[疾病名称]的临床真菌学特征和皮肤镜特征。

方法

我们评估了连续14例临床诊断为[疾病名称]的患者,这些患者10%氢氧化钾(KOH)检查和培养均为阳性,观察时间为6个月。所有患者均进行了皮肤镜检查。每个患者的人口统计学、临床和真菌学特征都记录在预先设计的表格上。

结果

有7名男性和7名女性患者,平均年龄27.6岁,平均病程3.8个月。所有患者都有使用强效或超强效外用类固醇的病史,使用时间长短不一,有的还联合使用了口服/注射类固醇。培养分离出的菌株在11例患者中为[某种复合真菌],3例患者中为[另一种真菌]。皮肤镜分析显示大多数患者有类固醇滥用的特征。

局限性

样本量小是我们研究的局限性。

结论

[疾病名称]是由于不当和不恰当地使用外用类固醇引起的[某种疾病]的一个特殊子集。其典型表现应提醒皮肤科医生注意可能存在的类固醇滥用情况。培养中分离出的最常见菌种是[某种复合真菌]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad6a/6615389/747e100e103c/IDOJ-10-422-g001.jpg

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