Katsikeris N, Kakarantza-Angelopoulou E, Angelopoulos A P
Department of Oral Pathology and Surgery, Dental School, University of Athens, Greece.
Int J Oral Maxillofac Surg. 1988 Apr;17(2):94-9. doi: 10.1016/s0901-5027(88)80158-9.
The clinical and histopathological features of 224 new cases of peripheral giant cell granuloma were studied. In addition, the data from 956 previously reported cases in the literature were evaluated and compared with the present series. Females were found to be more commonly affected than males. All age groups were found to be affected with a relative predilection from 40 to 60 years of age. The mandible was more often affected than the maxilla. Clinically, the lesions were red in color, had a smooth surface and were rubbery or with a soft consistency. The most characteristic histologic features included a non-encapsulated highly cellular mass with abundant giant cells, inflammation, interstitial hemorrhage, hemosiderin deposits, mature bone or osteoid.
对224例外周巨细胞肉芽肿新病例的临床和组织病理学特征进行了研究。此外，对文献中先前报道的956例病例的数据进行了评估，并与本系列病例进行了比较。发现女性比男性更易受累。所有年龄组均有发病，40至60岁相对更易发病。下颌骨比上颌骨更常受累。临床上，病变呈红色，表面光滑，质地似橡胶或柔软。最具特征性的组织学特征包括一个无包膜的高细胞性肿块，伴有大量巨细胞、炎症、间质出血、含铁血黄素沉积、成熟骨或类骨质。
