Ayoub Noel, Sunwoo John B, Starmer Heather M
Department of Otolaryngology, Head and Neck Surgery, Stanford University, Palo Alto, CA, 94305, USA.
World J Otorhinolaryngol Head Neck Surg. 2019 Feb 23;5(2):105-111. doi: 10.1016/j.wjorl.2018.09.006. eCollection 2019 Jun.
Patients living with human immunodeficiency virus (PLWH) are at higher risk of developing human papillomavirus (HPV)-associated malignancies. This prospective, longitudinal study evaluated the baseline knowledge of PLWH regarding HPV infection and its association with head neck cancer, and it aimed to determine whether a focused educational session could promote both short- and long-term knowledge acquisition in this population. Twenty-seven subjects participated in an interactive educational session and completed pre-test and immediate and delayed (4-month) post-test questionnaires. When compared to their pre-test answers, subjects demonstrated significant improvements in all 28 questions immediately following education. Knowledge preservation was demonstrated 4 months after initial evaluation, with subjects performing significantly better than their pre-test scores in 24 of the original 28 questions. These results suggest that short, focused, educational programs for PLWH may promote a better understanding of HPV's association with human immunodeficiency virus (HIV) and HPV risk factors, methods of transmission, and prevention.
感染人类免疫缺陷病毒（HIV）的患者患人乳头瘤病毒（HPV）相关恶性肿瘤的风险更高。这项前瞻性纵向研究评估了HIV感染者对HPV感染及其与头颈癌关联的基线知识，旨在确定一次针对性的教育课程是否能促进该人群短期和长期知识的获取。27名受试者参加了一次互动式教育课程，并完成了预测试以及即时和延迟（4个月后）后测试问卷。与预测试答案相比，受试者在教育结束后立即在所有28个问题上都有显著进步。在初次评估4个月后，知识得以保留，在最初的28个问题中，受试者在其中24个问题上的表现明显优于预测试分数。这些结果表明，针对HIV感染者的简短、有针对性的教育项目可能会促进对HPV与人类免疫缺陷病毒（HIV）的关联以及HPV风险因素、传播方式和预防方法的更好理解。
