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为低接种率学校量身定制的通用人乳头瘤病毒(HPV)疫苗接种计划教育包的共同制作:一项参与式研究方案。

Co-production of an educational package for the universal human papillomavirus (HPV) vaccination programme tailored for schools with low uptake: a participatory study protocol.

机构信息

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

出版信息

BMJ Open. 2020 Nov 4;10(11):e039029. doi: 10.1136/bmjopen-2020-039029.

Abstract

AIM

To co-produce with young people an educational package about the human papillomavirus (HPV) vaccine that is tailored to increase vaccine uptake in schools and populations with lower uptake.

INTRODUCTION

Persistent infection with HPV can result in cancers affecting men and especially women. From September 2019, the English-schools-based HPV vaccination programme was expanded to include young men (in addition to young women) aged 12-13 years. Some young people attending schools with lower uptake of the vaccine have unmet information needs. We hypothesise that mechanisms to address information needs and increase young people's autonomy in consent procedures will result in higher uptake.

METHODS AND ANALYSIS

The Medical Research Council's framework for development and evaluation of complex interventions will inform intervention development. Recruitment of young people aged 12-15 years and key stakeholders (National Health Service commissioners, school staff, immunisation nurses and youth workers/practitioners) will be facilitated through existing links with healthcare organisations, schools and youth organisations in areas with lower uptake of the HPV vaccination programme. The proposed research will comprise three phases: (1) a rapid review of adolescent immunisation materials and preliminary qualitative interviews with young people and key stakeholders, (2) theory development and co-production of HPV vaccine communication materials through an iterative process with young people and (iii) testing delivery mechanisms and acceptability of the educational package in four schools with lower uptake.

ETHICS AND DISSEMINATION

The University of Bristol's Faculty of Health Sciences and London School of Hygiene and Tropical Medicine's Research Ethics Committees provided approvals for the study. A dissemination event for young people and key stakeholders and webinar with the National Immunisation Network will be organised. The study findings will be published in peer-reviewed journals and presented at conferences. Recommendations for a future larger scale study will be made.

摘要

目的

与年轻人共同制作一个关于人乳头瘤病毒(HPV)疫苗的教育包,该疫苗专门用于提高学校和接种率较低人群的疫苗接种率。

背景

HPV 的持续感染可导致男性(尤其是女性)癌症。自 2019 年 9 月以来,以英语学校为基础的 HPV 疫苗接种计划已扩大到包括 12-13 岁的年轻男性(除年轻女性外)。一些在接种疫苗率较低的学校就读的年轻人有未满足的信息需求。我们假设,解决信息需求和增加年轻人在同意程序中的自主权的机制将导致更高的接种率。

方法和分析

医学研究委员会(MRC)制定和评估复杂干预措施的框架将为干预措施的制定提供信息。通过与医疗保健组织、学校和青年组织的现有联系,将方便招募年龄在 12-15 岁的年轻人和主要利益相关者(国家卫生服务专员、学校工作人员、免疫接种护士和青年工作者/从业者)。拟议的研究将包括三个阶段:(1)对青少年免疫材料进行快速审查,并对年轻人和主要利益相关者进行初步定性访谈;(2)通过与年轻人的迭代过程发展 HPV 疫苗传播理论和共同制作沟通材料;(3)在接种率较低的四所学校中测试教育包的交付机制和可接受性。

伦理和传播

布里斯托大学健康科学学院和伦敦卫生与热带医学学院的研究伦理委员会为该研究提供了批准。将组织一次针对年轻人和主要利益相关者的传播活动和一次与国家免疫网络的网络研讨会。研究结果将发表在同行评议的期刊上,并在会议上发表。将提出未来更大规模研究的建议。

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