饮食习惯与肝移植后体重过度增加有关。

Eating behaviour patterns are associated with excessive weight gain after liver transplantation.

机构信息

Food Science Post Graduation Program, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Nutrition Department, Universidade Federal do Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.

出版信息

J Hum Nutr Diet. 2019 Dec;32(6):693-701. doi: 10.1111/jhn.12661. Epub 2019 Jul 23.

DOI:10.1111/jhn.12661

PMID:31334582

Abstract

BACKGROUND

Weight gain and obesity are important issues in liver transplant (LTx) recipients. Although dietary habits are probably related to excessive weight gain after LTx, some studies have failed to demonstrate these associations. The present study aimed to assess eating behaviour and verify its association with weight gain and excessive weight among LTx recipients.

METHODS

The investigation comprised a cross-sectional study. Post-LTx patients, aged >18 years were evaluated about their eating behaviour [Three Factor Eating Questionnaire-R21 (TFEQ-R21)]. The scores of the TFEQ-R21 [uncontrolled eating (UE), cognitive restraint (CR) and emotional eating (EE)] were determined. Excessive weight was classified as body mass index ≥25 kg/m² and obesity ≥30 kg/m².

RESULTS

In total, 270 patients (age 58.0 years; range 20.0-77.0 years; 64.1% men) were assessed. Average weight gain was 8.0 kg (range -16.0 to 41.0 kg). Of the patients, 64.1% (n = 173) had excessive weight and 23.3% (n = 63) were obese. Post-LTx weight gain was significantly correlated with UE (r = 0.311, P < 0.001) and EE (r = 0.287, P < 0.001). Patients with excessive weight had significantly higher scores than others: CR (61.0; range 0-122.0 versus 44.0; range 0-116.0) (P = 0.003) and EE (11.0; range 0-100.0 versus 0.0; range 0-100.0) (P = 0.030). Patients with obesity had higher scores than non-obese UE (22.0; range 0-77.0 versus 14.0; range 0-85.0; P = 0.028), CR (55.0; range 11.0-116.0 versus 50.0; range 0-122.0) (P = 0.017) and EE (16.0; range 0-100.0 versus 5.0; range 0-100.0) individuals (P < 0.001). The greatest quartiles of weight gain had higher scores on the eating behaviours of UE and EE, especially those with weight gain ≥14 kg. UE was associated with weight gain. CR was associated with being overweight. EE was associated with obesity.

CONCLUSIONS

Uncontrolled eating is associated with weight gain, CR was associated with excessive weight and EE was associated with obesity after LTx.

摘要

背景

体重增加和肥胖是肝移植（LTx）受者的重要问题。尽管饮食习惯可能与 LTx 后体重过度增加有关，但一些研究未能证明这些关联。本研究旨在评估饮食行为，并验证其与 LTx 受者的体重增加和超重之间的关系。

方法

本研究包括一项横断面研究。对年龄>18 岁的 LTx 后患者进行饮食行为评估[三因素饮食问卷-R21（TFEQ-R21）]。确定 TFEQ-R21[失控饮食（UE）、认知约束（CR）和情绪性饮食（EE）]的得分。超重定义为体重指数≥25kg/m²，肥胖定义为≥30kg/m²。

结果

共评估了 270 名患者（年龄 58.0 岁；范围 20.0-77.0 岁；64.1%为男性）。平均体重增加 8.0kg（范围-16.0 至 41.0kg）。64.1%（n=173）的患者体重超重，23.3%（n=63）为肥胖。LTx 后体重增加与 UE（r=0.311，P<0.001）和 EE（r=0.287，P<0.001）显著相关。体重超重的患者得分明显高于其他患者：CR（61.0；范围 0-122.0 与 44.0；范围 0-116.0）（P=0.003）和 EE（11.0；范围 0-100.0 与 0.0；范围 0-100.0）（P=0.030）。肥胖患者的 UE（22.0；范围 0-77.0 与 14.0；范围 0-85.0）、CR（55.0；范围 11.0-116.0 与 50.0；范围 0-122.0）和 EE（16.0；范围 0-100.0 与 5.0；范围 0-100.0）得分明显高于非肥胖患者（P=0.028、P=0.017 和 P<0.001）。体重增加最多的四分位数患者 UE 和 EE 得分更高，尤其是体重增加≥14kg 的患者。UE 与体重增加相关。CR 与超重有关。EE 与肥胖有关。