Gastroenterology Unit, Department of Medical Specialties, University Hospital of Modena, University of Modena & Reggio Emilia, 41121 Modena, Italy.
Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, 41121 Modena, Italy.
Nutrients. 2023 Jun 16;15(12):2778. doi: 10.3390/nu15122778.
Liver transplantation (LT) is a complex surgical procedure requiring thorough pre- and post-operative planning and care. The nutritional status of the patient before, during, and after LT is crucial to surgical success and long-term prognosis. This review aims to assess nutritional status assessment and management before, during, and after LT, with a focus on patients who have undergone bariatric surgery. We performed a comprehensive topic search on MEDLINE, Ovid, In-Process, Cochrane Library, EMBASE, and PubMed up to March 2023. It identifies key factors influencing the nutritional status of liver transplant patients, such as pre-existing malnutrition, the type and severity of liver disease, comorbidities, and immunosuppressive medications. The review highlights the importance of pre-operative nutritional assessment and intervention, close nutritional status monitoring, individualised nutrition care plans, and ongoing nutritional support and monitoring after LT. The review concludes by examining the effect of bariatric surgery on the nutritional status of liver transplant recipients. The review offers valuable insights into the challenges and opportunities for optimising nutritional status before, during, and after LT.
肝移植(LT)是一种复杂的外科手术,需要进行彻底的术前和术后规划和护理。LT 前后患者的营养状况对手术成功和长期预后至关重要。本综述旨在评估 LT 前后的营养状况评估和管理,重点关注接受过减重手术的患者。我们对 MEDLINE、Ovid、In-Process、Cochrane 图书馆、EMBASE 和 PubMed 进行了全面的主题搜索,截至 2023 年 3 月。它确定了影响肝移植患者营养状况的关键因素,如术前营养不良、肝病的类型和严重程度、合并症和免疫抑制药物。该综述强调了术前营养评估和干预、密切的营养状况监测、个体化营养护理计划以及 LT 后持续的营养支持和监测的重要性。该综述通过检查减重手术对肝移植受者营养状况的影响,来结束讨论。该综述为优化 LT 前后的营养状况提供了有价值的见解,同时也提出了挑战和机遇。