Adult Health Post Graduate Program, Medical School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Transplantation. 2011 Oct 27;92(8):947-51. doi: 10.1097/TP.0b013e31822e0bee.
Overweight is often used as a description after liver transplantation (LTx), but studies on body composition of patients submitted to LTx have only been devoted to early postoperative periods; there is little information regarding abdominal obesity after LTx. The aim of this study was to assess body composition, body mass index (BMI), and waist circumference and verify the prevalence and risk factors for excessive weight, obesity, and abdominal obesity in long-term survivors of LTx.
Post-LTx patients with at least 1 year post-LTx were assessed for their body composition (by bioimpedance), BMI, and waist circumference. Demographic, socioeconomic, lifestyle, and clinical and dietetic variables were collected to assess risk factors using linear and logistic regression analyses.
We evaluated 143 patients (51±13 years; 59.4% male; median time since LTx: 4 years). The majority of patients had excessive weight, considering BMI, (58.1%). Considering body composition, 69.9% of patients were overweight and 37.8% obese. Some degree of abdominal obesity was seen in 88% of patients. Independent risk factors for overweight, obesity, and abdominal obesity after LTx included greater BMI before liver disease, weight gain since LTx, family history of overweight, smoking, working, being married, having less time since transplantation, a lower calcium intake, and less sleeping hours.
The majority of patients are overweight or obese after LTx, and many of the associated risk factors are modifiable. Thus, patients, especially those who already have identified risk factors for overweight and obesity, undergoing LTx should be encouraged to engage in lifestyle changes early.
超重通常在肝移植（LTx）后被用作描述，但对接受 LTx 的患者身体成分的研究仅专注于术后早期；关于 LTx 后腹部肥胖的信息较少。本研究的目的是评估身体成分、体重指数（BMI）和腰围，并验证 LTx 长期存活者超重、肥胖和腹型肥胖的患病率和危险因素。
对至少有 1 年 LTx 后患者进行身体成分（生物阻抗法）、BMI 和腰围评估。收集人口统计学、社会经济学、生活方式、临床和饮食变量，以使用线性和逻辑回归分析评估危险因素。
我们评估了 143 名患者（51±13 岁；59.4%为男性；LTx 后中位时间：4 年）。大多数患者的 BMI 表明存在超重（58.1%）。从身体成分来看，69.9%的患者超重，37.8%肥胖。88%的患者存在不同程度的腹型肥胖。LTx 后超重、肥胖和腹型肥胖的独立危险因素包括：肝病前 BMI 较高、LTx 后体重增加、超重家族史、吸烟、工作、已婚、LTx 后时间较短、钙摄入量较低和睡眠时间较少。
大多数 LTx 后患者超重或肥胖，许多相关危险因素是可以改变的。因此，应鼓励患者，特别是那些已经有超重和肥胖危险因素的患者，在 LTx 后早期进行生活方式改变。
