鼻孤立性角化棘皮瘤的病灶内注射甲氨蝶呤治疗及文献综述

Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature.

作者信息

Doerfler Laura, Hanke C. William

出版信息

J Drugs Dermatol. 2019 Jul 1;18(7):693-696.

Abstract

Keratoacathoma (KA) is a unique clinical pathological entity that is difficult to categorize. Differentiating a KA from a squamous cell carcinoma (SCC) is important for treatment implications but is often challenging. We report a patient with a solitary KA of the skin of the right ala successfully treated with intralesional (IL) injections of methotrexate (MTX). We also provide a review of the literature on IL-MTX as a treatment modality for KA. J Drugs Dermatol. 2019;18(7):693-696.

摘要

角化棘皮瘤（KA）是一种独特的临床病理实体，难以进行分类。将KA与鳞状细胞癌（SCC）区分开来对于治疗具有重要意义，但往往具有挑战性。我们报告了一名右鼻翼皮肤单发KA患者，通过病灶内（IL）注射甲氨蝶呤（MTX）成功治愈。我们还对病灶内注射甲氨蝶呤作为KA治疗方式的文献进行了综述。《皮肤药物学杂志》。2019年；18（7）：693 - 696。