From the Department of Medical Imaging, University of Arizona College of Medicine, Tucson, Arizona.
Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona.
ASAIO J. 2020 May;66(5):547-552. doi: 10.1097/MAT.0000000000001046.
Accurate right ventricle functional analysis prior to mechanical circulatory support continues to be valuable for preoperative stratification of patients at risk for developing right ventricular (RV) failure. While cardiac magnetic resonance imaging (CMR) remains the gold standard, CMR is limited by availability and patient-specific contraindications. Further investigation of other imaging modalities would be beneficial as it may serve as a surrogate to identifying RV systolic dysfunction. A single-center, retrospective study including 29 patients with advanced heart failure was performed. All patients underwent ventricular functional analysis with both CMR and echocardiography, and 19 patients underwent right heart catheterization. Predictability with multimodal assessment of RV function was determined using logistic regression methods. Of the 29 participants, 10 had severe RV dysfunction. Tricuspid annular plane of systolic excursion was a modest predictor of RV dysfunction with odd ratio (OR) of 0.07 (0.01-0.72) and c-statistic of 0.79. Invasive hemodynamic measurement of cardiac index by thermodilution method was also predictive of RV dysfunction but failed to reach statistical significance (OR of 0.03, <0.001-1.28) with c-statistic of 0.83. The role of invasive hemodynamic data in predicting RV function compared with CMR should be further explored among patients with advanced heart failure.
在接受机械循环支持之前,准确的右心室功能分析对于术前评估有发生右心室(RV)衰竭风险的患者仍然具有重要价值。虽然心脏磁共振成像(CMR)仍然是金标准,但 CMR 受到可用性和患者特定禁忌症的限制。进一步研究其他成像方式将是有益的,因为它可能作为识别 RV 收缩功能障碍的替代方法。对 29 名患有晚期心力衰竭的患者进行了一项单中心回顾性研究。所有患者均接受 CMR 和超声心动图进行心室功能分析,19 名患者接受右心导管检查。使用逻辑回归方法确定 RV 功能多模式评估的预测能力。在 29 名参与者中,有 10 名患有严重的 RV 功能障碍。三尖瓣环平面收缩期位移是 RV 功能障碍的适度预测因子,比值比(OR)为 0.07(0.01-0.72),C 统计量为 0.79。热稀释法测量的心脏指数的有创血流动力学测量也可以预测 RV 功能障碍,但 C 统计量为 0.83,未达到统计学意义(OR 为 0.03,<0.001-1.28)。在晚期心力衰竭患者中,有创血流动力学数据在预测 RV 功能方面与 CMR 相比的作用应进一步探讨。